There are 7 ways to get from La Serena to Uyuni by plane, shuttle, bus, helicopter, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Calama Airport, shuttle, Tour
best- Fly from La Florida Airport (LSC) to Calama Airport (CJC)plane LSC - CJC
- Take a shuttle bus from Calama Airport to San Pedro de Atacama
- Take a shuttle bus from San Pedro de Atacama to Uyuni
6h 55m$450–622Bus
cheapest- Take the bus from Terminal de buses La Serena to Terminal Rodoviario Calamabus Santiago Borja / ...
- Take the bus from Terminal Rodoviario Calama to Uyunibus Calama
22h 50m$55–106Bus, helicopter, Tour
- Take the bus from Terminal de buses La Serena to Antofagastabus
- Take the helicopter from Antofagasta Airport to San Pedro de Atacama Airporthelicopter Anf
- Take a shuttle bus from San Pedro de Atacama to Uyuni
16h 44m$9,203–9,224Drive 1,449.2 km
- Drive from La Serena to Uyunicar 1,449.2 km
18h 55m$179–259Fly to Uyuni Airport
- Fly from La Florida Airport (LSC) to Uyuni Airport (UYU)plane LSC - UYU
11h 24m$209–702Fly to Antofagasta Airport, helicopter, Tour
- Fly from La Florida Airport (LSC) to Antofagasta Airport (ANF)plane LSC - ANF
- Take the helicopter from Antofagasta Airport to San Pedro de Atacama Airporthelicopter
- Take a shuttle bus from San Pedro de Atacama to Uyuni
6h 56m$9,201–9,330Bus via Calama
- Take the bus from Terminal de buses La Serena to Terminal de Buses Calamabus La Serena
- Take the bus from Terminal de Buses Calama to Uyuníbus San Pedro
24h$79–132
La Florida Airport (LSC) to Calama Airport (CJC) flights
Questions & Answers
The cheapest way to get from La Serena to Uyuni is to bus which costs $55 - $110 and takes 22h 50m.
The fastest way to get from La Serena to Uyuni is to fly and shuttle and Tour which takes 6h 55m and costs $450 - $650.
No, there is no direct bus from La Serena to Uyuni. However, there are services departing from Terminal de buses La Serena and arriving at Uyuni via Terminal Rodoviario Calama. The journey, including transfers, takes approximately 22h 50m.
The distance between La Serena and Uyuni is 1353 km. The road distance is 1449.2 km.
The best way to get from La Serena to Uyuni without a car is to bus and helicopter and Tour which takes 16h 44m and costs $9,200 - $9,230.
It takes approximately 6h 55m to get from La Serena to Uyuni, including transfers.
La Serena to Uyuni bus services, operated by Turbus, depart from Terminal de buses La Serena station.
The best way to get from La Serena to Uyuni is to fly which takes 11h 24m and costs $200 - $700. Alternatively, you can bus, which costs $55 - $110 and takes 22h 50m.
La Serena to Uyuni bus services, operated by Turbus, arrive at Terminal Rodoviario Calama station.
Yes, the driving distance between La Serena to Uyuni is 1449 km. It takes approximately 18h 55m to drive from La Serena to Uyuni.
What companies run services between La Serena, Chile and Uyuni, Potosí, Bolivia?
LATAM Chile, Boliviana de Aviación, and Sky Airline fly from La Florida Airport (LSC) to Uyuni Airport (UYU) 3 times a week. Alternatively, you can take a bus from Terminal de buses La Serena to Uyuni via Terminal Rodoviario Calama in around 22h 50m.
- Website
- jetsmart.com
Flights from La Florida Airport to Calama Airport
- Ave. Duration
- 1h 30m
- When
- Wednesday, Thursday, Monday, Tuesday, Sunday, and Friday
- Estimated price
- $30–180
Flights from La Florida Airport to Antofagasta Airport
- Ave. Duration
- 1h 21m
- When
- Tuesday, Friday, Wednesday, Thursday, Sunday, and Monday
- Estimated price
- $40–170
- Website
- skyairline.com
Flights from La Florida Airport to Calama Airport
- Ave. Duration
- 1h 27m
- When
- Sunday, Wednesday, Tuesday, and Monday
- Estimated price
- $40–230
Flights from La Florida Airport to Antofagasta Airport
- Ave. Duration
- 1h 19m
- When
- Sunday, Monday, and Wednesday
- Estimated price
- $50–230
- Website
- boa.bo
Flights from La Florida Airport to Uyuni Airport via Santiago, La Paz
- Ave. Duration
- 22h 10m
- When
- Friday
- Estimated price
- $270–950
Flights from La Florida Airport to Uyuni Airport via Santiago, Santa Cruz, La Paz
- Ave. Duration
- 11h 20m
- When
- Friday
- Estimated price
- $340–1,000
Flights from La Florida Airport to Uyuni Airport via Iquique, Santa Cruz, La Paz
- Ave. Duration
- 20h 19m
- When
- Wednesday
- Estimated price
- $200–700
- Website
- latam.com
Flights from La Florida Airport to Calama Airport
- Ave. Duration
- 1h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–200
Flights from La Florida Airport to Antofagasta Airport
- Ave. Duration
- 1h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–480
- Phone
- +56 2 2677 3000
- [email protected]
- Website
- transvip.cl
Shuttle from Calama Airport to San Pedro de Atacama
- Ave. Duration
- 1h 22m
- Frequency
- Every 20 minutes
- Estimated price
- $9
- Book at
- transvip.cl
- Phone
- +56 9 6136 2282
- [email protected]
- Website
- cordilleratraveller.com
Shuttle from Calama Airport to San Pedro de Atacama
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $110
- Website
- https://cordilleratraveller.com/en/home-cordillera-traveller-english/
Shuttle from San Pedro de Atacama to Uyuni
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $300
- Website
- https://cordilleratraveller.com/en/home-cordillera-traveller-english/
Shuttle from San Pedro de Atacama to Uyuni
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $300
- Website
- https://cordilleratraveller.com/en/home-cordillera-traveller-english/
Shuttle from San Pedro de Atacama to Uyuni
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $300
- Website
- https://cordilleratraveller.com/en/home-cordillera-traveller-english/
Bus from Terminal de buses La Serena to Antofagasta
- Ave. Duration
- 10h 48m
- Frequency
- Every 4 hours
- Estimated price
- $24–45
- Schedules at
- cormarbus.cl
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario Calama
- Ave. Duration
- 14h 50m
- Frequency
- 3 times a day
- Estimated price
- $27–80
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $27–40
- Cama
- $40–60
- Premium
- $65–80
- Website
- https://www.flixbus.cl/
Bus from Terminal de buses La Serena to Terminal Rodoviario Calama
- Ave. Duration
- 14h 40m
- Frequency
- 3 times a day
- Estimated price
- $100–180
- Schedules at
- flixbus.cl
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario Calama
- Ave. Duration
- 15h 55m
- Frequency
- Once daily
- Estimated price
- $43–62
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $43–47
- Phone
- +𝟱𝟲 𝟵 𝟲𝟲𝟱𝟭 𝟮𝟯𝟱𝟮
- Website
- facebook.com
Bus from Terminal Rodoviario Calama to Uyuni
- Ave. Duration
- 7h
- Frequency
- 3 times a day
- Estimated price
- $28
- Website
- https://www.ticketsbolivia.com.bo/empresa/trans-ricardo.php
- Phone
- +56 22 683 8528
- [email protected]
- Website
- flixbus.cl
Bus from Terminal de buses La Serena to Terminal de Buses Calama
- Ave. Duration
- 15h
- Frequency
- Twice daily
- Estimated price
- $23–55
- Schedules at
- flixbus.cl
- Semi Cama
- $23–29
- Cama
- $30–55
- Phone
- +56 9 8149 3691
- [email protected]
Bus from Terminal de Buses Calama to Uyuní
- Ave. Duration
- 8h
- Frequency
- 4 times a week
- Estimated price
- $55–80
- Book at
- ticketsbolivia.com
- Road
- $55–80
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