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How to get fromLa Spezia to Karlsruheby train (Trenitalia), bus, car, train, plane, or night train

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There are 12 ways to get from La Spezia to Karlsruhe by train (Trenitalia), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from La Spezia Centrale to Milano Centraletrain train Ic
    2. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    10h 41m
    €104–205

  2. Bus

    cheapest
    1. Take the bus from La Spezia to Genoabus bus N503 / ...
    2. Take the bus from Genoa to Karlsruhe central train stationbus bus FlixBus N177
    13h 30m
    €63–109

  3. Drive 750.2 km

    1. Drive from La Spezia to Karlsruhecar car 750.2 km
    7h 28m
    €117–168

  4. Train to Pisa International Airport, fly to Frankfurt, train

    1. Take the train from La Spezia Centrale to Pisa Centraletrain train
    2. Fly from Pisa International Airport (PSA) to Frankfurt (FRA)plane plane PSA - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    6h 44m
    €127–426

  5. Train via Basel

    1. Take the train from La Spezia Centrale to Milano Centraletrain train Ic
    2. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    3. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    10h 51m
    €114–320

  6. Train, night train

    1. Take the train from La Spezia Centrale to Como Camerlatatrain train
    2. Take the train from Lugano to Zürich HBtrain train Ic2 / ...
    3. Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    12h 3m
    €104–346

  7. Train, train to Milano Malpensa Airport, fly to Stuttgart Airport

    1. Take the train from La Spezia Centrale to Milano Centraletrain train
    2. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane plane MXP - STR
    4. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    9h 11m
    €111–314

  8. Train, train to Florence Peretola Airport, fly to Frankfurt

    1. Take the train from La Spezia Centrale to Pisa Centraletrain train
    2. Take the train from Pisa Centrale to Firenze S.M.N.train train
    3. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    4. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    8h 26m
    €153–467

  9. Train, train to Milan Linate Airport, fly to Frankfurt

    1. Take the train from La Spezia Centrale to Vogheratrain train
    2. Take the train from Voghera to Milano Forlaninitrain train
    3. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    4. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    9h 25m
    €66–290

  10. Train, train to Milano Malpensa Airport, fly to Zurich Airport

    1. Take the train from La Spezia Centrale to Milano Centraletrain train
    2. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    4. Take the train from Zürich HB to Basel SBBtrain train
    5. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    10h 15m
    €161–497

  11. Train, train to Bologna Guglielmo Marconi Airport, fly to Frankfurt

    1. Take the train from La Spezia Centrale to Pisa Centraletrain train
    2. Take the train from Pisa Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    4. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane plane BLQ - FRA
    5. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    8h 54m
    €135–495

  12. Train, train to Florence Peretola Airport, fly to Zurich Airport

    1. Take the train from La Spezia Centrale to Pisa Centraletrain train
    2. Take the train from Pisa Centrale to Firenze S.M.N.train train
    3. Fly from Florence Peretola Airport (FLR) to Zurich Airport (ZRH)plane plane FLR - ZRH
    4. Take the train from Zürich HB to Basel SBBtrain train
    5. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    9h 40m
    €187–603

La Spezia to Karlsruhe by train (Trenitalia)

Calendar16Weekly Trains
Duration10h 41mAverage Duration
Ticket€104Cheapest Price
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Questions & Answers

Map of how to get from La Spezia to Karlsruhe.ExpandLaunch map view
  • Distance: 756 km
  • Duration: 10h 41m

What companies run services between La Spezia, Italy and Karlsruhe, Germany?

You can take a train from La Spezia Centrale to Karlsruhe Hbf via Milano Centrale in around 10h 41m. Alternatively, you can take a bus from La Spezia to Karlsruhe central train station via Genoa in around 13h 30m.

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