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How to get fromLaSalle to St. Louisby car, plane, bus (Greyhound), train (Amtrak), or bus (Amtrak, Flixbus)

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There are 6 ways to get from LaSalle to St. Louis by car, plane, bus (Greyhound), train (Amtrak), or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Detroit, fly

    best
    1. Drive from LaSalle to Detroit-Airport-DTWcar car
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    2h 59m
    $119–711

  2. Bus

    cheapest
    1. Take the bus from Detroit to Indianapolisbus bus Bsb 15
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 38m
    $69–138

  3. Train (Amtrak)

    1. Take the train from Dearborn to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    11h 7m
    $294–476

  4. Drive  522.4 mi

    1. Drive from LaSalle to St. Louiscar car 522.4 mi
    9h 4m
    $120–173

  5. Fly from Windsor Airport

    1. Fly from Windsor Airport (YQG) to Lambert–St. Louis International Airport (STL)plane plane YQG - STL
    6h 47m
    $179–884

  6. Bus via Chicago

    1. Take the bus from Detroit to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    14h 12m

Detroit (DTW) to Lambert–St. Louis International Airport (STL) flights

Calendar59Weekly Planes
Duration2h 9mAverage Duration
Ticket$114Cheapest Price
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Comparing Your Travel Options

Map of how to get from LaSalle to St. Louis.ExpandLaunch map view
  • Distance: 478.5 mi
  • Duration: 2h 59m

What companies run services between LaSalle, ON, Canada and St. Louis, MO, USA?

You can take a vehicle from LaSalle to St Louis Bus Station via Detroit and Indianapolis Union Station in around 10h 38m. Alternatively, you can take a vehicle from LaSalle to St. Louis via Dearborn and Chicago Union Station in around 11h 7m.

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Need to know: Greyhound

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