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How to get fromLady Lake to Florida Keysby taxi, plane, car, train, bus, shuttle, or bus (Greyhound)

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There are 12 ways to get from Lady Lake to Florida Keys by taxi, plane, car, train, bus, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Orlando Sanford, fly to Key West International Airport

    best
    1. Take the taxi from Lady Lake to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    5h 19m
    $230–473

  2. Drive 399.2 mi

    cheapest
    1. Drive from Lady Lake to Florida Keyscar car 399.2 mi
    8h 7m
    $73–106

  3. Drive, train, bus

    1. Drive from Lady Lake to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    11h 6m
    $93–257

  4. Shuttle to Orlando, fly to Key West International Airport

    1. Take a shuttle bus from Lake Sumter Depot to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    6h 54m
    $192–817

  5. Shuttle to Tampa, fly to Key West International Airport

    1. Take a shuttle bus from Lake Sumter Depot to Tampa International Airport - Red Terminalshuttle bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    7h 53m
    $217–732

  6. Shuttle to Orlando, fly to Miami International Airport, shuttle

    1. Take a shuttle bus from Lake Sumter Depot to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Miami International Airport (MIA)plane plane MCO - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 27m
    $752–1,357

  7. Shuttle to Orlando, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take a shuttle bus from Lake Sumter Depot to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MCO - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 54m
    $472–927

  8. Shuttle to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport

    1. Take a shuttle bus from Lake Sumter Depot to Tampa International Airport - Red Terminalshuttle bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    9h 49m
    $183–428

  9. Bus

    1. Take the bus from Ocala, FL to Miami Airportbus bus Tallahassee
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    12h 40m
    $161–260

  10. Bus, train

    1. Take the bus from Ocala, FL to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    13h 11m
    $146–241

  11. Bus, shuttle

    1. Take the bus from Wildwood to Miamibus bus Houston
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    14h 59m
    $262–324

  12. Bus, train via Lakeland

    1. Take the bus from The Villages-Lady Lake Amtrak Bus Stop to Lakelandbus bus
    2. Take the train from Lakeland to Fort Lauderdale Amtrak Stationtrain train
    3. Take the train from Fort Lauderdale Station to Miami Airport Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    15h 14m
    $132–246

Orlando Sanford (SFB) to Key West International Airport (EYW) flights

Calendar4Weekly Planes
Duration1h 17mAverage Duration
Ticket$38Cheapest Price
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Questions & Answers

Map of how to get from Lady Lake to Florida Keys.ExpandLaunch map view
  • Distance: 365.1 mi
  • Duration: 5h 19m

What companies run services between Lady Lake, FL, USA and Florida Keys, FL, USA?

You can take a vehicle from Lady Lake to Florida Keys via Ocala, FL, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 40m.

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