There are 10 ways to get from Lady Lake to Greenville by shuttle, plane, bus (Flixbus), taxi, train, bus, car, bus (Amtrak, Flixbus, Greyhound), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Orlando, fly to Greenville–Spartanburg International Airport
best- Take a shuttle bus from Lake Sumter Depot to MCO Airport - Terminal A
- Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane MCO - GSP
4h 46m$225–818Drive 460.7 mi
cheapest- Drive from Lady Lake to Greenvillecar 460.7 mi
9h 54m$85–122Bus via Atlanta
- Take the bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Drbus
- Take the bus from Gainesville to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
15h 4m$191–363Taxi, train, bus
- Take the taxi from Lady Lake to Delandtaxi
- Take the train from Deland to Carytrain
- Take the train from Cary to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
21h 42m$390–785Taxi to Orlando Sanford, fly to Asheville Regional Airport, taxi
- Take the taxi from Lady Lake to Orlando-Sanford-Airport-SFBtaxi
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
3h 48m$313–649Shuttle to Tampa, fly to Greenville–Spartanburg International Airport
- Take a shuttle bus from Lake Sumter Depot to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane TPA - GSP
5h 43m$190–463Taxi to Orlando Sanford, fly to Greenville–Spartanburg International Airport
- Take the taxi from Lady Lake to Orlando-Sanford-Airport-SFBtaxi
- Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane SFB - GSP
2h 56m$233–674Bus
- Take the bus from The Villages-Lady Lake Amtrak Bus Stop to Jacksonvillebus
- Take the bus from Jacksonville to Charlotte Bus Stationbus
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
16h 44m$167–354Bus via Gainesville
- Take the bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Drbus
- Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
16h 54m$191–373Bus via Jacksonville
- Take the bus from The Villages-Lady Lake Amtrak Bus Stop to Jacksonvillebus
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
17h 15m$173–361
Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Lady Lake to Greenville is to drive which costs $80 - $130 and takes 9h 54m.
The fastest way to get from Lady Lake to Greenville is to taxi and fly which takes 2h 56m and costs $230 - $700.
No, there is no direct bus from Lady Lake to Greenville. However, there are services departing from Ocala, FL and arriving at Taqueria Guadalajara - Greenville via Reitz Union, Gainesville and Atlanta. The journey, including transfers, takes approximately 15h 4m.
The distance between Lady Lake and Greenville is 536 miles. The road distance is 463.4 miles.
The best way to get from Lady Lake to Greenville without a car is to bus via Atlanta which takes 15h 4m and costs $190 - $370.
It takes approximately 4h 46m to get from Lady Lake to Greenville, including transfers.
Lady Lake to Greenville bus services, operated by RedCoach, depart from Ocala, FL station.
Lady Lake to Greenville bus services, operated by RedCoach, arrive at University of Florida - 1956 Gale Lemerand Dr station.
Yes, the driving distance between Lady Lake to Greenville is 463 miles. It takes approximately 9h 54m to drive from Lady Lake to Greenville.
There are 226+ hotels available in Greenville.
What companies run services between Lady Lake, FL, USA and Greenville, SC, USA?
You can take a vehicle from Lady Lake to Greenville via Ocala, FL, University of Florida - 1956 Gale Lemerand Dr, Reitz Union, Rosa Parks RTS Downtown Station, Gainesville, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 15h 4m.
- Website
- delta.com
Flights from Orlando to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $85–480
Flights from Tampa to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Orlando to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $85–480
Flights from Orlando to Greenville–Spartanburg International Airport via Miami
- Ave. Duration
- 4h 17m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
Flights from Tampa to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $100–600
Flights from Tampa to Greenville–Spartanburg International Airport via Miami
- Ave. Duration
- 4h 18m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–650
- Website
- allegiantair.com
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $55–340
Flights from Orlando Sanford to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 28m
- When
- Thursday and Sunday
- Estimated price
- $80–490
- Website
- southwest.com
Flights from Orlando to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 11m
- When
- Sunday and Saturday
- Estimated price
- $110–600
Flights from Tampa to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Tuesday and Wednesday
- Estimated price
- $130–650
- Website
- flybreeze.com
Flights from Orlando to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 41m
- When
- Monday and Friday
- Estimated price
- $140–750
Flights from Tampa to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 41m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $75–220
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Deland to Cary
- Ave. Duration
- 12h 35m
- Frequency
- Once daily
- Estimated price
- $180–390
- Website
- Amtrak
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $50–110
- Website
- Amtrak
- Phone
- +1 352 539 9664
- Website
- Groome Transportation
Shuttle from Lake Sumter Depot to MCO Airport - Terminal A
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $35–55
- Website
- Groome Transportation
- online discount
- $35–50
- call in
- $40–55
Shuttle from Lake Sumter Depot to Tampa International Airport - Red Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- $50–70
- Website
- Groome Transportation
- online discount
- $50–65
- call in
- $55–70
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- RedCoach
Bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- RedCoach
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Every 4 hours
- Estimated price
- $50–90
- Schedules at
- Flixbus USA
Bus from Jacksonville to Charlotte Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- Twice daily
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Every 4 hours
- Estimated price
- $60–110
- Schedules at
- Flixbus USA
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from The Villages-Lady Lake Amtrak Bus Stop to Jacksonville
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Amtrak
Bus from The Villages-Lady Lake Amtrak Bus Stop to Jacksonville
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Jacksonville to Charlotte Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Gainesville Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $50–100
- Website
- Greyhound
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- Greyhound
- Ave. Duration
- 1h 6m
- Estimated price
- $100–170
A-1 Taxi
- Phone
- +1 352-753-1415
A-1 Taxi
- Phone
- +1 352-753-1415
Asheville Taxi
- Phone
- +1 828-333-1976
- Website
- avltaxi.com
A-1 Taxi
- Phone
- +1 352-753-1415
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