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How to get fromLady Lake to Knoxvilleby taxi, plane, bus, shuttle, car, or train

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There are 7 ways to get from Lady Lake to Knoxville by taxi, plane, bus, shuttle, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Orlando Sanford, fly to Mcghee Tyson Airport

    best
    1. Take the taxi from Lady Lake to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3h 5m
    $283–859

  2. Drive 584.8 mi

    cheapest
    1. Drive from Lady Lake to Knoxvillecar car 584.8 mi
    10h 2m
    $107–155

  3. Bus, taxi, shuttle, drive

    1. Take the bus from The Villages-Lady Lake Amtrak Bus Stop to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Chilhowee at Holstoncar car
    22h 8m

  4. Taxi, train, bus, shuttle, drive

    1. Take the taxi from Lady Lake to Delandtaxi taxi
    2. Take the train from Deland to Carytrain train
    3. Take the train from Cary to High Pointtrain train
    4. Take the bus from Forsyth Hospital to Boonebus bus
    5. Take the taxi from Boone to Black Bear Resorttaxi taxi
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    25h 45m

  5. Shuttle to Orlando, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Lake Sumter Depot to MCO Airport - Terminal Ashuttle bus
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    4h 44m
    $205–743

  6. Taxi to Orlando Sanford, fly to Asheville Regional Airport, drive

    1. Take the taxi from Lady Lake to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    4h 58m
    $195–504

  7. Bus, train, shuttle, drive

    1. Take the bus from The Villages-Lady Lake Amtrak Bus Stop to Jacksonvillebus bus
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte to Boonebus bus
    5. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    25h 59m

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

Map of how to get from Lady Lake to Knoxville.ExpandLaunch map view
  • Distance: 574.9 mi
  • Duration: 3h 5m

What companies run services between Lady Lake, FL, USA and Knoxville, TN, USA?

There is no direct connection from Lady Lake to Knoxville. However, you can take the taxi to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to The Villages-Lady Lake Amtrak Bus Stop, take the bus to Jacksonville, walk to Amtrak Station, take the line 4 bus to JRTC Bay H, walk to Jacksonville, take the bus to Charlotte Bus Station, take the bus to Boone, take the taxi to Black Bear Resort, take the shuttle to Hot Springs, drive to Chilhowee at Holston, then take the line 31 bus to Knoxville Station Hall of Fame.

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