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How to get fromLafayette to Charlestonby shuttle, plane, bus (Amtrak, Greyhound), train (Amtrak), car, bus, or train

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There are 7 ways to get from Lafayette to Charleston by shuttle, plane, bus (Amtrak, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Indianapolis, fly

    best
    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Charleston International Airport (CHS)plane plane IND - CHS
    7h 37m
    $102–515

  2. Fly from Purdue University Airport

    cheapest
    1. Fly from Purdue University Airport (LAF) to Charleston International Airport (CHS)plane plane LAF - CHS
    7h 58m
    $93–463

  3. Bus

    1. Take the bus from Lafayette Amtrak Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    28h 52m
    $163–346

  4. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Alexandriatrain train Cardinal
    2. Take the train from Alexandria to Charleston Amtrak Stationtrain train Silver Meteor / ...
    30h 47m
    $423–880

  5. Drive 754.9 mi

    1. Drive from Lafayette to Charlestoncar car 754.9 mi
    13h 55m
    $138–199

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    7h 23m
    $558–873

  7. Train to Chicago Midway International Airport, fly

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    8h 54m
    $139–588

Lafayette to Charleston by bus

Calendar7Weekly Buses
Duration28h 52mAverage Duration
Ticket$163Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to Charleston.ExpandLaunch map view
  • Distance: 668.9 mi
  • Duration: 7h 37m

What companies run services between Lafayette, IN, USA and Charleston, SC, USA?

You can take a bus from Lafayette Amtrak Station to Transit Mall via Indianapolis Union Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 28h 52m. Alternatively, you can take a train from Lafayette Amtrak Station to Charleston via Alexandria and Charleston Amtrak Station in around 30h 47m.

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