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How to get fromLafayette to Ithacaby shuttle, plane, bus (Amtrak, Flixbus), train, bus, car, or bus (Amtrak, Greyhound)

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There are 10 ways to get from Lafayette to Ithaca by shuttle, plane, bus (Amtrak, Flixbus), train, bus, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Indianapolis, fly to Ithaca Tompkins Regional Airport

    best
    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Ithaca Tompkins Regional Airport (ITH)plane plane IND - ITH
    7h 50m
    $110–513

  2. Bus via Cleveland

    cheapest
    1. Take the bus from Lafayette Amtrak Station to Gary, INbus bus
    2. Take the bus from Gary to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    4. Take the bus from Buffalo to Ithacabus bus
    18h 20m
    $93–223

  3. Train, bus

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    19h 31m
    $259–536

  4. Drive 631.5 mi

    1. Drive from Lafayette to Ithacacar car 631.5 mi
    11h 39m
    $116–167

  5. Shuttle to Indianapolis, fly to Elmira/Corning Regional Airport, bus

    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Elmira/Corning Regional Airport (ELM)plane plane IND - ELM
    3. Take the bus from Transit Center - PO Side to Tompkins County Librarybus bus
    9h 34m
    $100–482

  6. Fly Purdue University Airport to Syracuse Hancock International Airport, bus

    1. Fly from Purdue University Airport (LAF) to Syracuse Hancock International Airport (SYR)plane plane LAF - SYR
    2. Take the bus from Syracuse Bus Station to Ithacabus bus
    9h 34m
    $154–795

  7. Bus to Chicago O'Hare International Airport, fly to Rochester, bus

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)plane plane ORD - ROC
    3. Take the bus from Rochester to Ithacabus bus
    8h 18m
    $195–750

  8. Bus to Chicago O'Hare International Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)plane plane ORD - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    8h 46m
    $189–765

  9. Train to Chicago Midway International Airport, fly to Rochester, bus

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    3. Take the bus from Rochester to Ithacabus bus
    9h 51m
    $213–916

  10. Bus

    1. Take the bus from Lafayette Amtrak Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg, Pa to Scranton, Pabus bus 770
    4. Take the bus from Scranton, Pa to Ithacabus bus 246
    25h 25m
    $145–352

Lafayette to Ithaca by bus

Calendar7Weekly Buses
Duration18h 20mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to Ithaca.ExpandLaunch map view
  • Distance: 622 mi
  • Duration: 7h 50m

What companies run services between Lafayette, IN, USA and Ithaca, NY, USA?

You can take a bus from Lafayette Amtrak Station to Ithaca via Gary, Cleveland, OH, Buffalo, NY, and Buffalo in around 18h 20m.

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