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How to get fromLafayette to Lancasterby bus, plane, bus (Amtrak, Greyhound), train (Amtrak), car, shuttle, train, or bus (Amtrak, Flixbus)

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There are 6 ways to get from Lafayette to Lancaster by bus, plane, bus (Amtrak, Greyhound), train (Amtrak), car, shuttle, train, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly to Lancaster

    best
    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane plane ORD - LNS
    5h 49m
    $139–453

  2. Bus

    cheapest
    1. Take the bus from Lafayette Amtrak Station to Indianapolis Union Stationbus bus Chicago
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus Greyhound US0421
    20h 52m
    $99–213

  3. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to 30th Street Stationtrain train Cardinal
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train Keystone Service / ...
    27h 22m
    $310–652

  4. Drive 632 mi

    1. Drive from Lafayette to Lancastercar car 632 mi
    11h 2m
    $116–167

  5. Shuttle to Indianapolis, fly to Philadelphia International Airport, train

    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Philadelphia International Airport (PHL)plane plane IND - PHL
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    9h 25m
    $154–891

  6. Bus via Gary

    1. Take the bus from Lafayette Amtrak Station to Gary, INbus bus
    2. Take the bus from Gary Bus Station to Harrisburg Bus Stationbus bus FlixBus N2642
    23h 2m
    $134–244

Lafayette to Lancaster by bus and train

Calendar7Weekly Services
Duration20h 52mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to Lancaster.ExpandLaunch map view
  • Distance: 765.2 mi
  • Duration: 5h 49m

What companies run services between Lafayette, IN, USA and Lancaster, PA, USA?

You can take a bus from Lafayette Amtrak Station to W. Chestnut & Water St. via Indianapolis Union Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 20h 52m. Alternatively, you can take a train from Lafayette Amtrak Station to W. Chestnut & Water St. via 30th Street Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 27h 22m.

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