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How to get fromLafayette to Myrtle Beachby shuttle, plane, bus (Amtrak, Greyhound, Flixbus), train, bus, or car

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There are 9 ways to get from Lafayette to Myrtle Beach by shuttle, plane, bus (Amtrak, Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Indianapolis, fly

    best
    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Myrtle Beach (MYR)plane plane IND - MYR
    6h 6m
    $96–437

  2. Fly from Purdue University Airport

    cheapest
    1. Fly from Purdue University Airport (LAF) to Myrtle Beach (MYR)plane plane LAF - MYR
    7h 29m
    $87–385

  3. Bus

    1. Take the bus from Lafayette Amtrak Station to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    23h
    $142–251

  4. Train, bus via Arlington

    1. Take the train from Lafayette Amtrak Station to Alexandriatrain train
    2. Take the train from Alexandria to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    33h 49m
    $429–876

  5. Drive 778.2 mi

    1. Drive from Lafayette to Myrtle Beachcar car 778.2 mi
    14h 31m
    $142–206

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    5h 55m
    $132–425

  7. Train to Chicago Midway International Airport, fly

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane plane MDW - MYR
    7h 23m
    $135–521

  8. Bus, shuttle

    1. Take the bus from Courtyard Lafayette to Indianapolis Airportbus bus
    2. Take a shuttle bus from Indianapolis Airport to The Graduate Hotelshuttle bus
    3. Take the bus from Bloomington to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    24h 25m
    $195–317

  9. Train, bus

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    40h 8m
    $446–961

Lafayette to Myrtle Beach by bus

Calendar7Weekly Buses
Duration23hAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to Myrtle Beach.ExpandLaunch map view
  • Distance: 654.3 mi
  • Duration: 6h 6m

What companies run services between Lafayette, IN, USA and Myrtle Beach, SC, USA?

You can take a bus from Lafayette Amtrak Station to Myrtle Beach Bus Station via Nashville Bus Station and Atlanta Bus Station in around 23h. Alternatively, United Airlines and American Airlines fly from Purdue University Airport (LAF) to Myrtle Beach (MYR) twice daily.

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Train operators
Bus operators

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