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How to get fromLafayette to San Antonioby shuttle, plane, bus (Amtrak), bus, train, or car

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There are 8 ways to get from Lafayette to San Antonio by shuttle, plane, bus (Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Indianapolis, fly to San Antonio International Airport

    best
    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to San Antonio International Airport (SAT)plane plane IND - SAT
    7h 26m
    $447–1,135

  2. Fly Purdue University Airport to San Antonio International Airport

    cheapest
    1. Fly from Purdue University Airport (LAF) to San Antonio International Airport (SAT)plane plane LAF - SAT
    9h 24m
    $143–703

  3. Bus

    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago to Tornado Bus Co - San Antoniobus bus Chicago
    28h 43m
    $209–389

  4. Bus, train (Amtrak)

    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to San Antonio Stationtrain train Texas Eagle
    35h 56m
    $424–894

  5. Drive 1,154.3 mi

    1. Drive from Lafayette to San Antoniocar car 1,154.3 mi
    19h 45m
    $211–305

  6. Bus to Chicago O'Hare International Airport, fly to San Antonio International Airport

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to San Antonio International Airport (SAT)plane plane ORD - SAT
    7h 4m
    $228–623

  7. Train to Chicago Midway International Airport, fly to San Antonio International Airport

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to San Antonio International Airport (SAT)plane plane MDW - SAT
    8h 37m
    $194–838

  8. Shuttle to Indianapolis, fly to Austin-Bergstrom International Airport, bus

    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Austin-Bergstrom International Airport (AUS)plane plane IND - AUS
    3. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    8h 16m
    $418–1,060

Lafayette to San Antonio by bus

Calendar7Weekly Buses
Duration28h 43mAverage Duration
Ticket$209Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to San Antonio.ExpandLaunch map view
  • Distance: 1,062.5 mi
  • Duration: 7h 26m

What companies run services between Lafayette, IN, USA and San Antonio, TX, USA?

You can take a bus from Lafayette Amtrak Station to S. St. Mary's & Nueva via Chicago Union Station, Clinton & Jackson, Cicero & 24th Place Terminal, Chicago, Tornado Bus Co - San Antonio, and I-35 S Access & Yarrow Blvd in around 28h 43m. Alternatively, United Airlines and American Airlines fly from Purdue University Airport (LAF) to San Antonio International Airport (SAT) 4 times a day.

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