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How to get fromLafayette to Sioux Fallsby plane, bus (Amtrak, Greyhound), train, bus, car, shuttle, or bus (Flixbus)

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There are 9 ways to get from Lafayette to Sioux Falls by plane, bus (Amtrak, Greyhound), train, bus, car, shuttle, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Purdue University Airport

    best
    1. Fly from Purdue University Airport (LAF) to Sioux Falls (FSD)plane plane LAF - FSD
    6h 41m
    $68–363

  2. Bus

    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Omaha, NEbus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    19h 22m
    $146–261

  3. Train, bus via Minneapolis

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from Minneapolis to Sioux Fallsbus bus
    20h 39m
    $237–454

  4. Drive 662.8 mi

    1. Drive from Lafayette to Sioux Fallscar car 662.8 mi
    12h 21m
    $121–175

  5. Shuttle to Indianapolis, fly

    1. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Sioux Falls (FSD)plane plane IND - FSD
    7h 59m
    $102–495

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Sioux Falls (FSD)plane plane ORD - FSD
    6h 37m
    $113–403

  7. Train to Chicago Midway International Airport, fly

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Sioux Falls (FSD)plane plane MDW - FSD
    10h 10m
    $120–529

  8. Bus via Minneapolis

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    3. Take the bus from Milwaukee Mitchell Airport to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Sioux Fallsbus bus
    20h 58m
    $213–306

  9. Train, bus

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from Minneapolis-St. Paul to Sioux Fallsbus bus
    22h 27m
    $247–464

Purdue University Airport (LAF) to Sioux Falls (FSD) flights

Calendar18Weekly Planes
Duration5h 59mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to Sioux Falls.ExpandLaunch map view
  • Distance: 556.7 mi
  • Duration: 6h 41m

What companies run services between Lafayette, IN, USA and Sioux Falls, SD, USA?

United Airlines flies from Purdue University Airport (LAF) to Sioux Falls (FSD) 3 times a day. Alternatively, you can take a bus from Lafayette Amtrak Station to The Bus Stop via Chicago Union Station, Chicago Bus Station, Omaha, Sioux Falls, and Maple/Career NE corner in around 19h 22m.

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