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How to get fromLafayette to Des Moinesby plane, bus (Greyhound), bus, train, car, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Lafayette to Des Moines by plane, bus (Greyhound), bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lafayette Regional Airport

    best
    1. Fly from Lafayette Regional Airport (LFT) to Des Moines (DSM)plane plane LFT - DSM
    5h
    $178–784

  2. Drive 895.7 mi

    cheapest
    1. Drive from Lafayette to Des Moinescar car 895.7 mi
    16h 51m
    $164–237

  3. Bus via Wake Village

    1. Take the bus from Lafayette Transit System to Shreveport Bus Stationbus bus
    2. Take the bus from Shreveport Bus Station to Texarkanabus bus
    3. Take the bus from Texarkana to Kansas Citybus bus
    4. Take the bus from Kansas City to Des Moinesbus bus
    22h 30m
    $212–334

  4. Bus, train

    1. Take the bus from Lafayette to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus bus
    28h 45m
    $322–686

  5. Bus to Lake Charles Regional Airport, fly

    1. Take the bus from Lafayette to Lake Charlesbus bus
    2. Fly from Lake Charles Regional Airport (LCH) to Des Moines (DSM)plane plane LCH - DSM
    6h 44m
    $222–839

  6. Bus

    1. Take the bus from Lafayette to Baton Rouge Bus Stationbus bus
    2. Take the bus from Baton Rouge Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    28h 15m
    $179–365

Lafayette to Des Moines by bus

Calendar11Weekly Buses
Duration22h 30mAverage Duration
Ticket$212Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to Des Moines.ExpandLaunch map view
  • Distance: 797 mi
  • Duration: 5h

What companies run services between Lafayette, LA, USA and Des Moines, IA, USA?

American Airlines, United Airlines, and Delta fly from Lafayette Regional Airport (LFT) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Lafayette Transit System to Des Moines via Shreveport Bus Station, Texarkana, and Kansas City in around 22h 30m.

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Bus operators

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