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How to get fromLafayette to San Antonioby bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound, Flixbus), or bus

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There are 6 ways to get from Lafayette to San Antonio by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Lafayette to San Antonio Bus Stationbus bus FlixBus 2212
    7h 20m
    $60–100

  2. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to San Antonio Stationtrain train Sunset Limited
    11h 41m
    $130–280

  3. Drive 410 mi

    1. Drive from Lafayette to San Antoniocar car 410 mi
    6h 41m
    $75–109

  4. Fly from Lafayette Regional Airport

    1. Fly from Lafayette Regional Airport (LFT) to San Antonio International Airport (SAT)plane plane LFT - SAT
    4h 27m
    $83–465

  5. Bus via Houston

    1. Take the bus from Lafayette Transit System to Houston Bus Stationbus bus Greyhound US0602 / ...
    2. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus Greyhound US1001 / ...
    8h 30m
    $61–121

  6. Bus to Lake Charles Regional Airport, fly

    1. Take the bus from Lafayette to Lake Charlesbus bus
    2. Fly from Lake Charles Regional Airport (LCH) to San Antonio International Airport (SAT)plane plane LCH - SAT
    6h 5m
    $122–500

Lafayette to San Antonio by bus (Flixbus)

Calendar5Weekly Buses
Duration7h 20mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Lafayette to San Antonio.ExpandLaunch map view
  • Distance: 409.1 mi
  • Duration: 7h 20m

What companies run services between Lafayette, LA, USA and San Antonio, TX, USA?

Flixbus USA operates a bus from Lafayette to San Antonio Bus Station 5 times a week. Tickets cost $60–100 and the journey takes 7h 20m. Alternatively, Amtrak operates a train from Lafayette Amtrak Station to San Antonio Station 3 times a week. Tickets cost $130–280 and the journey takes 11h 41m.

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