There are 4 ways to get from Lafayette to Sanibel Island by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Lafayette Regional Airport
best- Fly from Lafayette Regional Airport (LFT) to Ft. Myers (RSW)plane LFT - RSW
5h 34m$176–648Drive 875 mi
cheapest- Drive from Lafayette to Sanibel Islandcar 875 mi
15h 14m$160–231Bus
- Take the bus from Lafayette to Fort Myersbus Houston
17h 24m$200–251Bus to Louis Armstrong New Orleans International Airport, fly
- Take the bus from Lafayette Transit System to New Orleans International Airportbus
- Fly from Louis Armstrong New Orleans International Airport (MSY) to Ft. Myers (RSW)plane MSY - RSW
7h 4m$336–925
Lafayette Regional Airport (LFT) to Ft. Myers (RSW) flights
Questions & Answers
The cheapest way to get from Lafayette to Sanibel Island is to drive which costs $160 - $240 and takes 15h 14m.
The fastest way to get from Lafayette to Sanibel Island is to fly which takes 5h 34m and costs $170 - $650.
No, there is no direct bus from Lafayette to Sanibel Island. However, there are services departing from Lafayette and arriving at Fort Myers via . The journey, including transfers, takes approximately 17h 24m.
The distance between Lafayette and Sanibel Island is 702 miles. The road distance is 880.2 miles.
The best way to get from Lafayette to Sanibel Island without a car is to bus which takes 17h 24m and costs $200 - $260.
It takes approximately 5h 34m to get from Lafayette to Sanibel Island, including transfers.
Lafayette to Sanibel Island bus services, operated by Omnibus Express, depart from Lafayette station.
The best way to get from Lafayette to Sanibel Island is to fly which takes 5h 34m and costs $170 - $650. Alternatively, you can bus, which costs $200 - $260 and takes 17h 24m.
Lafayette to Sanibel Island bus services, operated by Omnibus Express, arrive at Fort Myers station.
Yes, the driving distance between Lafayette to Sanibel Island is 880 miles. It takes approximately 15h 14m to drive from Lafayette to Sanibel Island.
What companies run services between Lafayette, LA, USA and Sanibel Island, FL, USA?
Delta, United Airlines, and American Airlines fly from Lafayette Regional Airport (LFT) to Ft. Myers (RSW) every 4 hours. Alternatively, Omnibus Express operates a bus from Lafayette to Fort Myers once daily. Tickets cost $140–190 and the journey takes 16h 53m.
- Website
- delta.com
Flights from Lafayette Regional Airport to Ft. Myers via Atlanta
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $100–550
Flights from Louis Armstrong New Orleans International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
- Website
- aa.com
Flights from Lafayette Regional Airport to Ft. Myers via Dallas/Ft.Worth
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $130–600
Flights from Lafayette Regional Airport to Ft. Myers via Charlotte
- Ave. Duration
- 9h 41m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
- Website
- southwest.com
Flights from Louis Armstrong New Orleans International Airport to Ft. Myers via Orlando
- Ave. Duration
- 3h 52m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $100–550
- Website
- united.com
Flights from Lafayette Regional Airport to Ft. Myers via Houston
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $100–550
- Website
- flybreeze.com
Flights from Louis Armstrong New Orleans International Airport to Ft. Myers
- Ave. Duration
- 1h 45m
- When
- Wednesday and Saturday
- Estimated price
- $250–800
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Lafayette to Fort Myers
- Ave. Duration
- 16h 53m
- Frequency
- Once daily
- Estimated price
- $140–190
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Lafayette Transit System to New Orleans International Airport
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 3322+ hotels available in Sanibel Island.




