There are 11 ways to get from Lago di Como to Isernia by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Como S. Giovanni to Milano Centraletrain S11
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Iserniatrain Re
7h 16m€110–233Fly Milano Malpensa Airport to Naples Airport, train
cheapest- Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane MXP - NAP
- Take the train from Caserta to Iserniatrain
7h 23m€35–180Bus
- Take the bus from Como to Casello - A1 Ingresso Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
9h 50m€88–125Drive 773.7 km
- Drive from Como to Iserniacar 773.7 km
7h 19m€123–178Bus via Florence
- Take the bus from Como to Florence Villa Constanza Bus Stationbus 518
- Take the bus from Florence Villa Constanza Bus Station to Iserniabus 433
16h 59m€80–133Fly Milan Linate Airport to Naples Airport, train
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Caserta to Iserniatrain
7h 38m€74–220Fly Milan Linate Airport to Fiumicino International Airport, train
- Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane LIN - FCO
- Take the train from Roma Termini to Iserniatrain
7h 32m€82–229Train, bus to Il Caravaggio International Airport, fly to Naples Airport
- Take the train from Lecco to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane BGY - NAP
- Take the train from Caserta to Iserniatrain
7h 55m€62–264Fly Milano Malpensa Airport to Abruzzo Airport, bus
- Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane MXP - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
8h 2m€42–199Fly Milano Malpensa Airport to Salerno Costa D'Amalfi Airport, train
- Fly from Milano Malpensa Airport (MXP) to Salerno Costa D'Amalfi Airport (QSR)plane MXP - QSR
- Take the train from Salerno to Casertatrain
- Take the train from Caserta to Iserniatrain
9h 35m€54–216Train, bus to Il Caravaggio International Airport, fly to Abruzzo Airport, bus
- Take the train from Lecco to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Abruzzo Airport (PSR)plane BGY - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
8h 34m€56–263
Lago di Como to Isernia by train
Questions & Answers
The cheapest way to get from Lago di Como to Isernia is to fly and bus which costs €40 - €200 and takes 8h 2m.
The fastest way to get from Lago di Como to Isernia is to train which takes 7h 16m and costs €110 - €240.
No, there is no direct bus from Lago di Como to Isernia. However, there are services departing from Como - San Rocchetto and arriving at Isernia via Como and Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 9h 50m.
No, there is no direct train from Lago di Como to Isernia. However, there are services departing from Como S. Giovanni and arriving at Isernia via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 7h 16m.
The distance between Lago di Como and Isernia is 794 km. The road distance is 773.7 km.
The best way to get from Lago di Como to Isernia without a car is to train which takes 7h 16m and costs €110 - €240.
It takes approximately 7h 16m to get from Lago di Como to Isernia, including transfers.
Lago di Como to Isernia bus services, operated by FlixBus, depart from Como station.
Lago di Como to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
The best way to get from Lago di Como to Isernia is to train which takes 7h 16m and costs €110 - €240. Alternatively, you can bus, which costs €85 - €130 and takes 9h 50m.
What companies run services between Lago di Como, Italy and Isernia, Italy?
You can take a train from Como S. Giovanni to Isernia via Milano Centrale and Roma Termini in around 7h 16m. Alternatively, you can take a bus from Como - San Rocchetto to Isernia via Como - S. Zenone, Como, and Casello - A1 Ingresso Caianello in around 9h 50m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €30–150
Flights from Milano Malpensa Airport to Naples Airport via Alghero
- Ave. Duration
- 3h 45m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €30–150
Flights from Il Caravaggio International Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–200
Flights from Il Caravaggio International Airport to Naples Airport via Palermo
- Ave. Duration
- 3h 40m
- When
- Tuesday
- Estimated price
- €40–200
Flights from Milano Malpensa Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €27–180
Flights from Il Caravaggio International Airport to Abruzzo Airport
- Ave. Duration
- 1h 15m
- When
- Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €40–210
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €16–50
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Como to Casello - A1 Ingresso Caianello
- Ave. Duration
- 6h 47m
- Frequency
- Once a week
- Estimated price
- €85–120
- Website
- Onebus
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More Questions & Answers
Lago di Como to Isernia bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Lago di Como to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Lago di Como to Isernia is 774 km. It takes approximately 7h 19m to drive from Lago di Como to Isernia.
Book your Lago di Como to Isernia train tickets online with Omio.
Book your Lago di Como to Isernia bus tickets online with Omio and FlixBus.
There are 468+ hotels available in Isernia.



