There are 4 ways to get from Lago di Como to Siena by train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Como S. Giovanni to Milano Centraletrain S11
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
4h 55m€56–109Bus
- Take the bus from Como to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
6h 5m€67–96Drive 409 km
- Drive from Como to Sienacar 409 km
4h 17m€74–107Train, bus
- Take the train from Como S. Giovanni to Firenze S. M. N.train Ec
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
5h 57m€120–179
Lago di Como to Siena by train
Comparing Your Travel Options
The cheapest way to get from Lago di Como to Siena is to train which costs €55 - €110 and takes 4h 55m.
The fastest way to get from Lago di Como to Siena is to drive which takes 4h 17m and costs €70 - €110.
No, there is no direct bus from Lago di Como to Siena. However, there are services departing from Como - San Rocchetto and arriving at Siena via Como and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 6h 5m.
No, there is no direct train from Lago di Como to Siena. However, there are services departing from Como S. Giovanni and arriving at Siena via Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 4h 55m.
The distance between Lago di Como and Siena is 444 km. The road distance is 409 km.
The best way to get from Lago di Como to Siena without a car is to train which takes 4h 55m and costs €55 - €110.
It takes approximately 4h 55m to get from Lago di Como to Siena, including transfers.
Lago di Como to Siena bus services, operated by Onebus, depart from Como station.
Lago di Como to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
The best way to get from Lago di Como to Siena is to train which takes 4h 55m and costs €55 - €110. Alternatively, you can bus, which costs €65 - €100 and takes 6h 5m.
What companies run services between Lago di Como, Italy and Siena, Italy?
You can take a train from Como S. Giovanni to Siena via Milano Centrale and Firenze S.M.N. in around 4h 55m. Alternatively, you can take a bus from Como - San Rocchetto to Siena via Como - S. Zenone, Como, and Florence Villa Constanza Bus Station in around 6h 5m.
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €15–24
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Como S. Giovanni to Firenze S. M. N.
- Ave. Duration
- 4h 20m
- Frequency
- Once a week
- Estimated price
- €110–180
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 3m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Como to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Onebus
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €6–9
- Website
- Flixbus
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Lago di Como to Siena bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Lago di Como to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Lago di Como to Siena is 409 km. It takes approximately 4h 17m to drive from Lago di Como to Siena.
Book your Lago di Como to Siena train tickets online with Omio.
There are 2282+ hotels available in Siena.