There are 6 ways to get from Laguna Niguel to Palo Alto by plane, train, bus (Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Norman Y. Mineta San José International Airport, Caltrain
best- Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane SNA - SJC
- Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain
2h 37m$253–875Bus via Los Angeles
cheapest- Take the bus from Laguna Hills Trans Ctr Dock 5 to Fullerton Park And Ride Dock 5bus 83
- Take the bus from Fullerton Park & Ride Dock 14 to 6th / Los Angelesbus 460
- Take the bus from Los Angeles Downtown to San Josebus
16h 24m$57–81Bus (Greyhound)
- Take the bus from Santa Ana Bus Stop to San Jose Diridon Stationbus Greyhound US0831
10h 54m$64–121Train (Amtrak)
- Take the train from San Juan Capistrano Amtrak Station to Los Angelestrain Pacific Surfliner
- Take the train from Los Angeles to San Josetrain Coast Starlight
12h 56m$153–324Drive 407.4 mi
- Drive from Laguna Niguel to Palo Altocar 407.4 mi
6h 57m$75–108Fly to San Francisco International Airport, Caltrain
- Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane SNA - SFO
- Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain
2h 52m$249–784
Laguna Niguel to Palo Alto by bus and train (Greyhound)
Questions & Answers
The cheapest way to get from Laguna Niguel to Palo Alto is to bus via Los Angeles which costs $55 - $85 and takes 16h 24m.
The fastest way to get from Laguna Niguel to Palo Alto is to fly and Caltrain which takes 2h 37m and costs $250 - $900.
No, there is no direct bus from Laguna Niguel to Palo Alto station. However, there are services departing from Niguel-Crown Valley and arriving at San Jose Diridon Station via Laguna Hills Trans Ctr Dock 5 and Santa Ana Bus Stop. The journey, including transfers, takes approximately 10h 54m.
No, there is no direct train from Laguna Niguel station to Palo Alto. However, there are services departing from San Juan Capistrano Amtrak Station and arriving at California Avenue Caltrain Northbound via Los Angeles and San Jose Diridon Caltrain Northbound. The journey, including transfers, takes approximately 12h 56m.
The distance between Laguna Niguel and Palo Alto is 379 miles. The road distance is 409.8 miles.
The best way to get from Laguna Niguel to Palo Alto without a car is to bus which takes 10h 54m and costs $60 - $130.
It takes approximately 2h 37m to get from Laguna Niguel to Palo Alto, including transfers.
Laguna Niguel to Palo Alto bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
Laguna Niguel to Palo Alto train services, operated by Amtrak, depart from San Juan Capistrano Amtrak Station.
The best way to get from Laguna Niguel to Palo Alto is to bus which takes 10h 54m and costs $60 - $130. Alternatively, you can train, which costs $150 - $330 and takes 12h 56m.
What companies run services between Laguna Niguel, CA, USA and Palo Alto, CA, USA?
Greyhound USA operates a bus from Santa Ana Bus Stop to San Jose Diridon Station twice daily. Tickets cost $55–110 and the journey takes 8h 10m. Alternatively, you can take a train from San Juan Capistrano Amtrak Station to California Avenue Caltrain Northbound via Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 12h 56m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $50–340
Flights from John Wayne Airport Orange County to San Francisco International Airport via Las Vegas
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–270
- Website
- alaskaair.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $100–320
- Website
- united.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $35–230
- Website
- flyfrontier.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 41m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–290
- Phone
- +1 800-660-4287
- Website
- Cal Train
Train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northbound
- Ave. Duration
- 18 min
- Frequency
- Every 30 minutes
- Estimated price
- $4–6
- Website
- Cal Train
- Schedules at
- Cal Train
- One-way Adult
- $4–6
Train from Millbrae Caltrain Southbound to California Avenue Caltrain Southbound
- Ave. Duration
- 31 min
- Frequency
- Every 30 minutes
- Estimated price
- $5–7
- Website
- Cal Train
- Schedules at
- Cal Train
- One-way Adult
- $5–7
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Juan Capistrano Amtrak Station to Los Angeles
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $18–40
- Website
- Amtrak
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Santa Ana Bus Stop to San Jose Diridon Station
- Ave. Duration
- 8h 10m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- Greyhound
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Laguna Hills Trans Ctr Dock 5 to Fullerton Park And Ride Dock 5
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1-323-466-3876
- [email protected]
- Website
- Metro Los Angeles
Bus from Fullerton Park & Ride Dock 14 to 6th / Los Angeles
- Ave. Duration
- 1h 42m
- Frequency
- Every 30 minutes
- Estimated price
- $1–2
- Website
- Metro Los Angeles
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Los Angeles Downtown to San Jose
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $50–70
- Titanium
- $55–65
Want to know more about travelling around United States
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More Questions & Answers
Laguna Niguel to Palo Alto bus services, operated by Greyhound USA, arrive at San Jose Diridon Station.
Laguna Niguel to Palo Alto train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Laguna Niguel to Palo Alto is 410 miles. It takes approximately 6h 57m to drive from Laguna Niguel to Palo Alto.
There are 495+ hotels available in Palo Alto.


















