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How to get fromLaguna Niguel to San Franciscoby plane, train, bus, train (Amtrak), car, or bus (Greyhound)

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There are 7 ways to get from Laguna Niguel to San Francisco by plane, train, bus, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane plane SNA - SFO
    2h 22m
    $175–778

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Santa Ana Bus Stop to San Francisco Bus Stationbus bus Greyhound US0831
    11h 48m
    $64–134

  3. Train, bus

    1. Take the train from Laguna Niguel / Mission Viejo to L.A. Union Stationtrain train OC Line
    2. Take the bus from Los Angeles Union Station to San Franciscobus bus FlixBus 2005
    11h 13m
    $75–123

  4. Train, Caltrain

    1. Take the train from San Juan Capistrano Amtrak Station to Los Angelestrain train
    2. Take the train from Los Angeles to San Josetrain train
    3. Take the train from San Jose Diridon Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    13h 48m
    $157–329

  5. Drive 433.1 mi

    1. Drive from Laguna Niguel to San Franciscocar car 433.1 mi
    7h 17m
    $79–115

  6. Fly to Oakland International Airport

    1. Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane plane SNA - OAK
    2h 24m
    $271–824

  7. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane plane SNA - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    3h 31m
    $258–881

Laguna Niguel to San Francisco by train and bus

Calendar4Weekly Services
Duration11h 13mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Laguna Niguel to San Francisco.ExpandLaunch map view
  • Distance: 403.4 mi
  • Duration: 2h 22m

What companies run services between Laguna Niguel, CA, USA and San Francisco, CA, USA?

Frontier Airlines, Alaska Airlines, Inc., and two other airlines fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO) hourly. Alternatively, you can take a train from San Juan Capistrano Amtrak Station to San Francisco Caltrain Northbound via Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 13h 48m.

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