There are 5 ways to get from Lake Charles to St. Louis by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lake Charles Regional Airport (LCH) to Lambert–St. Louis International Airport (STL)plane LCH - STL
5h 5m$134–616Drive 704.1 mi
cheapest- Drive from Lake Charles to St. Louiscar 704.1 mi
13h 15m$129–186Bus
- Take the bus from Lake Charles to Baton Rouge Bus Stationbus Greyhound US0799
- Take the bus from Baton Rouge Bus Station to St Louis Bus Stationbus Greyhound US1173
20h 25m$140–279Bus, train
- Take the bus from Lake Charles to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Carbondaletrain
- Take the bus from Carbondale to St. Louisbus
20h 48m$248–514Train, bus
- Take the train from Lake Charles Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Carbondaletrain
- Take the bus from Carbondale to St. Louisbus
23h 39m$287–604
Lake Charles to St. Louis by bus
Questions & Answers
The cheapest way to get from Lake Charles to St. Louis is to drive which costs $120 - $190 and takes 13h 15m.
The fastest way to get from Lake Charles to St. Louis is to fly which takes 5h 5m and costs $130 - $650.
No, there is no direct bus from Lake Charles to St. Louis station. However, there are services departing from Lake Charles and arriving at St Louis Bus Station via Baton Rouge Bus Station. The journey, including transfers, takes approximately 20h 25m.
The distance between Lake Charles and St. Louis is 642 miles. The road distance is 708.2 miles.
The best way to get from Lake Charles to St. Louis without a car is to bus which takes 20h 25m and costs $140 - $280.
It takes approximately 5h 5m to get from Lake Charles to St. Louis, including transfers.
Lake Charles to St. Louis bus services, operated by Greyhound USA, depart from Lake Charles station.
The best way to get from Lake Charles to St. Louis is to fly which takes 5h 5m and costs $130 - $650. Alternatively, you can bus, which costs $140 - $280 and takes 20h 25m.
Lake Charles to St. Louis bus services, operated by Greyhound USA, arrive at Baton Rouge Bus Station.
Yes, the driving distance between Lake Charles to St. Louis is 708 miles. It takes approximately 13h 15m to drive from Lake Charles to St. Louis.
What companies run services between Lake Charles, LA, USA and St. Louis, MO, USA?
American Airlines and United Airlines fly from Lake Charles Regional Airport (LCH) to Lambert–St. Louis International Airport (STL) 3 times a day. Alternatively, you can take a bus from Lake Charles to St Louis Bus Station via Baton Rouge Bus Station in around 20h 25m.
- Website
- aa.com
Flights from Lake Charles Regional Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $120–600
- Website
- united.com
Flights from Lake Charles Regional Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 5h 29m
- When
- Monday, Wednesday, Thursday, Sunday, and Saturday
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New Orleans Union Passenger Terminal to Carbondale
- Ave. Duration
- 13h 28m
- Frequency
- Once daily
- Estimated price
- $200–410
- Website
- https://www.amtrak.com/home.html
Train from Lake Charles Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 6h 11m
- Frequency
- 3 times a week
- Estimated price
- $70–150
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Carbondale
- Ave. Duration
- 13h 28m
- Frequency
- Once daily
- Estimated price
- $200–410
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Lake Charles to Baton Rouge Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Baton Rouge Bus Station to St Louis Bus Station
- Ave. Duration
- 16h 55m
- Frequency
- Once daily
- Estimated price
- $120–240
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Lake Charles to Baton Rouge Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $20–35
- Schedules at
- flixbus.com
Bus from Lake Charles to New Orleans Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 5 times a week
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $15–25
- Schedules at
- flixbus.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $15–25
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Lake Charles to St. Louis bus tickets online with Omio and FlixBus.
There are 459+ hotels available in St. Louis.






