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How to get fromLake City to Biloxiby bus, plane, bus (Greyhound, Flixbus), or car

Find Transport to Biloxi

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There are 6 ways to get from Lake City to Biloxi by bus, plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Valdosta, fly to Gulfport-Biloxi Regional Airport

    best
    1. Take the bus from Lake City Bus Station to Valdostabus bus
    2. Fly from Valdosta (VLD) to Gulfport-Biloxi Regional Airport (GPT)plane plane VLD - GPT
    6h 29m
    $124–449

  2. Drive  403 mi

    cheapest
    1. Drive from Lake City to Biloxicar car 403 mi
    6h 37m
    $74–107

  3. Bus

    1. Take the bus from Lake City Bus Station to Mobile Bus Stationbus bus Greyhound US0760S
    2. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus Greyhound US0602
    11h 50m
    $75–114

  4. Bus to Jacksonville, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Gulfport-Biloxi Regional Airport (GPT)plane plane JAX - GPT
    8h
    $112–424

  5. Bus to Valdosta, fly to Mobile Regional Airport, bus

    1. Take the bus from Lake City Bus Station to Valdostabus bus
    2. Fly from Valdosta (VLD) to Mobile Regional Airport (MOB)plane plane VLD - MOB
    3. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    7h 58m
    $117–439

  6. Bus to Jacksonville, fly to Mobile Regional Airport, bus

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Mobile Regional Airport (MOB)plane plane JAX - MOB
    3. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    9h 52m
    $105–424

Lake City to Biloxi by bus

Calendar7Weekly Buses
Duration11h 50mAverage Duration
Ticket$75Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lake City to Biloxi.ExpandLaunch map view
  • Distance: 425.4 mi
  • Duration: 6h 29m

What companies run services between Lake City, FL, USA and Biloxi, MS, USA?

You can take a bus from Lake City Bus Station to Biloxi Transit Center via Mobile Bus Station in around 11h 50m.

Airlines
Bus operators

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