There are 7 ways to get from Lake City to Boston by bus, plane, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Theodore Francis Green State Airport, train
best- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to Theodore Francis Green State Airport (PVD)plane JAX - PVD
- Take the train from TF Green Airport to South Stationtrain
8h 48m$85–364Bus, train
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
26h 3m$306–758Bus
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Take the bus from Jacksonville to New York City Chinatownbus
- Take the bus from NYC Downtown to Bostonbus
26h 44m$190–295Drive 1,188.9 mi
- Drive from Lake City to Bostoncar 1,188.9 mi
20h 51m$217–314Bus, fly to John F. Kennedy International Airport, train
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to John F. Kennedy International Airport (JFK)plane JAX - JFK
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
11h$140–497Bus, fly to Laguardia Airport, train
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to Laguardia Airport (LGA)plane JAX - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
11h 16m$169–764Bus via Atlanta
- Take the bus from Lake City Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Port Authority Bus Terminalbus
- Take the bus from New York to Bostonbus
31h 42m$237–388
Lake City to Boston by bus and train
Comparing Your Travel Options
The cheapest way to get from Lake City to Boston is to bus and fly and train which costs $80 - $370 and takes 8h 48m.
The fastest way to get from Lake City to Boston is to bus and fly and train which takes 8h 48m and costs $80 - $370.
No, there is no direct bus from Lake City station to Boston. However, there are services departing from Lake City Bus Station and arriving at Boston via Jacksonville and NYC Downtown. The journey, including transfers, takes approximately 26h 44m.
The distance between Lake City and Boston is 1099 miles. The road distance is 1195.8 miles.
The best way to get from Lake City to Boston without a car is to bus and train which takes 26h 3m and costs $300 - $800.
It takes approximately 8h 48m to get from Lake City to Boston, including transfers.
Lake City to Boston bus services, operated by Greyhound USA, depart from Lake City Bus Station.
Lake City to Boston bus services, operated by Greyhound USA, arrive at Jacksonville station.
Yes, the driving distance between Lake City to Boston is 1196 miles. It takes approximately 20h 51m to drive from Lake City to Boston.
Book your Lake City to Boston bus tickets online with Omio and FlixBus.
What companies run services between Lake City, FL, USA and Boston, MA, USA?
You can take a bus from Lake City Bus Station to Boston via Jacksonville, New York City Chinatown, and NYC Downtown in around 26h 44m.
- Website
- aa.com
Flights from Jacksonville to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $65–330
Flights from Jacksonville to John F. Kennedy International Airport via Reagan Washington
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $60–320
Flights from Jacksonville to John F. Kennedy International Airport via Charlotte
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $60–330
Flights from Jacksonville to Laguardia Airport
- Ave. Duration
- 2h 27m
- When
- Saturday and Sunday
- Estimated price
- $100–600
Flights from Jacksonville to Laguardia Airport via Charlotte
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $110–600
Flights from Jacksonville to Laguardia Airport via Reagan Washington
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $100–600
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Lake City Bus Station to Atlanta Bus Station
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Atlanta Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 19h 25m
- Frequency
- 4 times a day
- Estimated price
- $150–240
- Website
- Greyhound
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