There are 5 ways to get from Lake City to Columbia by bus, train, bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Lake City Bus Station to Jacksonvillebus Greyhound US0760S
- Take the train from Jacksonville to Columbia Stationtrain Floridian
8h 34m$100–210Bus
cheapest- Take the bus from Lake City Bus Station to Jacksonvillebus
- Take the bus from Jacksonville to Sumter Bus Stopbus
- Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus 44
11h 6m$56–109Drive 342 mi
- Drive from Lake City to Columbiacar 342 mi
5h 47m$63–91Bus to Valdosta, fly
- Take the bus from Lake City Bus Station to Valdostabus
- Fly from Valdosta (VLD) to Columbia (CAE)plane VLD - CAE
6h 41m$154–887Bus to Jacksonville, fly
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to Columbia (CAE)plane JAX - CAE
8h 13m$172–972
Lake City to Columbia by bus and train
Questions & Answers
The cheapest way to get from Lake City to Columbia is to bus which costs $55 - $110 and takes 11h 6m.
The fastest way to get from Lake City to Columbia is to drive which takes 5h 47m and costs $60 - $90.
No, there is no direct bus from Lake City station to Columbia. However, there are services departing from Lake City Bus Station and arriving at Assembly Senate North via Jacksonville and James E Clyburn Intermodal Transportation Center. The journey, including transfers, takes approximately 11h 6m.
The distance between Lake City and Columbia is 354 miles. The road distance is 344 miles.
The best way to get from Lake City to Columbia without a car is to bus and train which takes 8h 34m and costs $100 - $210.
It takes approximately 8h 34m to get from Lake City to Columbia, including transfers.
Lake City to Columbia bus services, operated by Greyhound USA, depart from Lake City Bus Station.
Lake City to Columbia bus services, operated by Greyhound USA, arrive at Jacksonville station.
Yes, the driving distance between Lake City to Columbia is 344 miles. It takes approximately 5h 47m to drive from Lake City to Columbia.
There are 404+ hotels available in Columbia.
What companies run services between Lake City, FL, USA and Columbia, SC, USA?
You can take a bus from Lake City Bus Station to Assembly Senate North via Jacksonville, Sumter Bus Stop, and James E Clyburn Intermodal Transportation Center in around 11h 6m.
- Website
- delta.com
Flights from Valdosta to Columbia via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $130–850
Flights from Jacksonville to Columbia via Atlanta
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Jacksonville to Columbia via New York La Guardia
- Ave. Duration
- 7h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $360–1,600
- Website
- aa.com
Flights from Jacksonville to Columbia via Charlotte
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $160–950
Flights from Jacksonville to Columbia via Miami
- Ave. Duration
- 5h 30m
- When
- Saturday
- Estimated price
- $250–1,300
Flights from Jacksonville to Columbia via New York La Guardia
- Ave. Duration
- 7h 26m
- When
- Saturday and Sunday
- Estimated price
- $360–1,600
- Website
- united.com
Flights from Jacksonville to Columbia via Washington Dulles
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $280–1,300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Columbia Station
- Ave. Duration
- 5h 38m
- Frequency
- Once daily
- Estimated price
- $90–190
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Lake City Bus Station to Valdosta
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
- Phone
- +1 803-255-7100
- Website
- The COMET
Bus from James E Clyburn Intermodal Transportation Center to Assembly Senate North
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- The COMET
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide







