There are 4 ways to get from Lake City to Greenville by bus, plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Valdosta, fly
best- Take the bus from Lake City Bus Station to Valdostabus
- Fly from Valdosta (VLD) to Greenville–Spartanburg International Airport (GSP)plane VLD - GSP
5h 38m$132–550Drive 370.7 mi
cheapest- Drive from Lake City to Greenvillecar 370.7 mi
8h 10m$68–98Bus
- Take the bus from Lake City Bus Station to Atlanta Bus Stationbus Greyhound US0630
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus Charlotte
11h 23m$110–258Bus to Jacksonville, fly
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to Greenville–Spartanburg International Airport (GSP)plane JAX - GSP
7h 10m$435–665
Valdosta (VLD) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Lake City to Greenville is to drive which costs $65 - $100 and takes 8h 10m.
The fastest way to get from Lake City to Greenville is to bus and fly which takes 5h 38m and costs $130 - $550.
No, there is no direct bus from Lake City station to Greenville. However, there are services departing from Lake City Bus Station and arriving at Taqueria Guadalajara - Greenville via Lindbergh Center Station - Bay D and Atlanta. The journey, including transfers, takes approximately 11h 23m.
The distance between Lake City and Greenville is 371 miles. The road distance is 372.8 miles.
The best way to get from Lake City to Greenville without a car is to bus which takes 11h 23m and costs $110 - $260.
It takes approximately 5h 38m to get from Lake City to Greenville, including transfers.
Lake City to Greenville bus services, operated by Greyhound USA, depart from Lake City Bus Station.
Lake City to Greenville bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Lake City to Greenville is 373 miles. It takes approximately 8h 10m to drive from Lake City to Greenville.
There are 268+ hotels available in Greenville.
What companies run services between Lake City, FL, USA and Greenville, SC, USA?
You can take a bus from Lake City Bus Station to Greenville via Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 11h 23m.
- Website
- delta.com
Flights from Valdosta to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $75–470
Flights from Jacksonville to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Jacksonville to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 56m
- When
- Monday to Wednesday
- Estimated price
- $160–800
Flights from Jacksonville to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $120–700
- Website
- aa.com
Flights from Jacksonville to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Lake City Bus Station to Valdosta
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Atlanta Bus Station
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–17
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
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