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How to get fromLake City to Houstonby bus, plane, bus (Greyhound), train, car, or shuttle

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There are 6 ways to get from Lake City to Houston by bus, plane, bus (Greyhound), train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Jacksonville, fly to William P. Hobby Airport

    best
    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to William P. Hobby Airport (HOU)plane plane JAX - HOU
    7h 5m
    $84–401

  2. Bus (Greyhound)

    1. Take the bus from Lake City Bus Station to Tallahasseebus bus Greyhound US0760S
    2. Take the bus from Tallahassee to Houston Bus Stationbus bus Greyhound US0799
    19h 19m
    $150–230

  3. Bus, train

    1. Take the bus from Lake City Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Houstontrain train
    24h 58m
    $294–528

  4. Drive  811.4 mi

    1. Drive from Lake City to Houstoncar car 811.4 mi
    13h 9m
    $134–194

  5. Bus to Jacksonville, fly to George Bush Intercontinental Airport

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to George Bush Intercontinental Airport (IAH)plane plane JAX - IAH
    7h 30m
    $94–463

  6. Bus, shuttle to Tampa, fly to William P. Hobby Airport

    1. Take the bus from Lake City to Wildwoodbus bus
    2. Take a shuttle bus from Brownwood Hotel & Spa to Tampa International Airport - Red Terminalshuttle bus
    3. Fly from Tampa (TPA) to William P. Hobby Airport (HOU)plane plane TPA - HOU
    8h 45m
    $184–549

Lake City to Houston by bus (Greyhound)

Calendar7Weekly Buses
Duration19h 19mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lake City to Houston.ExpandLaunch map view
  • Distance: 901.4 mi
  • Duration: 7h 5m

What companies run services between Lake City, FL, USA and Houston, TX, USA?

You can take a bus from Lake City Bus Station to Congress St @ Milam St via Tallahassee, Houston Bus Station, and Magnolia Transit Center in around 19h 19m.

Airlines
Train operators
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Need to know: Greyhound

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