What is the cheapest way to get from Lake City to Knoxville?

The cheapest way to get from Lake City to Knoxville is to drive which costs $85 - $130 and takes 8h 17m.

What is the fastest way to get from Lake City to Knoxville?

The fastest way to get from Lake City to Knoxville is to drive and fly which takes 4h 57m and costs $190 - $800.

Is there a direct bus between Lake City and Knoxville?

No, there is no direct bus from Lake City station to Knoxville station. However, there are services departing from Lake City Bus Station and arriving at Knoxville Station Hall of Fame via Jacksonville, New York, NY, Walmart and Charlie Haun WB Aft Washington PK. The journey, including transfers, takes approximately 37h 40m.

How far is it from Lake City to Knoxville?

The distance between Lake City and Knoxville is 431 miles. The road distance is 487.6 miles.

How do I travel from Lake City to Knoxville without a car?

The best way to get from Lake City to Knoxville without a car is to bus and train via Farragut which takes 35h 8m and costs $500 - $950.

How long does it take to get from Lake City to Knoxville?

It takes approximately 5h 58m to get from Lake City to Knoxville, including transfers.

Where do I catch the Lake City to Knoxville bus from?

Lake City to Knoxville bus services, operated by Greyhound USA, depart from Lake City Bus Station.

Where does the Lake City to Knoxville bus arrive?

Lake City to Knoxville bus services, operated by Greyhound USA, arrive at Jacksonville station.

Can I drive from Lake City to Knoxville?

Yes, the driving distance between Lake City to Knoxville is 488 miles. It takes approximately 8h 17m to drive from Lake City to Knoxville.

Where can I stay near Knoxville?

There are 321+ hotels available in Knoxville.

Lake City to Knoxville - 8 ways to travel via train, bus, plane, and car

How to get fromLake City to Knoxville

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There are 8 ways to get from Lake City to Knoxville by bus, plane, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus to Valdosta, fly
best
1. Take the bus from Lake City Bus Station to Valdostabus
2. Fly from Valdosta (VLD) to Mcghee Tyson Airport (TYS)plane VLD - TYS
5h 58m
$167–705
Drive 484.8 mi
cheapest
1. Drive from Lake City to Knoxvillecar 484.8 mi
8h 17m
$89–128
Bus, train via Farragut
1. Take the bus from Lake City Bus Station to Jacksonvillebus
2. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain
3. Take the bus from New York to Knoxvillebus Nyc
35h 8m
$503–923
Bus
1. Take the bus from Lake City Bus Station to Jacksonvillebus
2. Take the bus from Jacksonville to New York City Chinatownbus
3. Take the bus from New York, NY to Knoxville, TNbus Ny
37h 40m
$268–402
Bus to Jacksonville, fly
1. Take the bus from Lake City Bus Station to Jacksonvillebus
2. Fly from Jacksonville (JAX) to Mcghee Tyson Airport (TYS)plane JAX - TYS
5h 8m
$175–740
Drive to Orlando Sanford, fly
1. Drive from Lake City to Orlando-Sanford-Airport-SFBcar
2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
4h 57m
$193–760
Bus, train
1. Take the bus from Lake City Bus Station to Jacksonvillebus
2. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain
3. Take the bus from New York, NY to Knoxville, TNbus Ny
35h 12m
$458–833
Bus via Atlanta
1. Take the bus from Lake City Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to New York City Chinatownbus
3. Take the bus from New York, NY to Knoxville, TNbus Ny
41h 47m
$294–449

Valdosta (VLD) to Mcghee Tyson Airport (TYS) flights

16Weekly Planes

3h 52mAverage Duration

$92Cheapest Price

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Questions & Answers

Map of how to get from Lake City to Knoxville.

Launch map view

Distance: 428.1 mi
Duration: 5h 58m

What companies run services between Lake City, FL, USA and Knoxville, TN, USA?

You can take a bus from Lake City Bus Station to Knoxville Station Hall of Fame via Jacksonville, New York, NY, Knoxville, TN, Walmart, and Charlie Haun WB Aft Washington PK in around 37h 40m.

Airlines

Train operators

Bus operators

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