There are 8 ways to get from Lake City to Naples by bus (Greyhound, Flixbus), car, bus, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via University
best- Take the bus from Lake City Bus Station to Jacksonvillebus
- Take the bus from Jacksonville to Gainesvillebus
- Take the bus from Gainesville to University of South Floridabus
- Take the bus from University of South Florida - 3801 USF Holly Dr to Naples, FLbus
11h 10m$100–182Drive 306 mi
cheapest- Drive from Lake City to Naplescar 306 mi
5h 53m$56–81Bus to Jacksonville, fly to Fort Lauderdale–Hollywood International Airport, bus
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to Fort Lauderdale–Hollywood International Airport (FLL)plane JAX - FLL
- Take the bus from Fort Lauderdale Airport to Naples, FLbus
7h 36m$177–697Bus
- Take the bus from Lake City to Fort Myersbus Houston
11h 25m$97–128Bus #2
- Take the bus from Lake City Bus Station to Tallahasseebus Greyhound US0760S
- Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Naples, FLbus Tallahassee
12h 29m$150–279Bus via Orlando
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Take the bus from Jacksonville to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus
15h 59m$63–123Bus to Jacksonville, fly to Miami International Airport, bus
- Take the bus from Lake City Bus Station to Jacksonvillebus
- Fly from Jacksonville (JAX) to Miami International Airport (MIA)plane JAX - MIA
- Take the bus from Miami Airport to Naples, FLbus
8h 10m$117–462Bus to Tallahassee, fly to Miami International Airport, bus
- Take the bus from Lake City Bus Station to Tallahasseebus
- Fly from Tallahassee (TLH) to Miami International Airport (MIA)plane TLH - MIA
- Take the bus from Miami Airport to Naples, FLbus
8h$152–511
Lake City to Naples by bus
Questions & Answers
The cheapest way to get from Lake City to Naples is to drive which costs $55 - $85 and takes 5h 53m.
The fastest way to get from Lake City to Naples is to drive which takes 5h 53m and costs $55 - $85.
No, there is no direct bus from Lake City station to Naples. However, there are services departing from Lake City Bus Station and arriving at Naples, FL via Jacksonville, Gainesville and University of South Florida - 3801 USF Holly Dr. The journey, including transfers, takes approximately 11h 10m.
The distance between Lake City and Naples is 431 miles. The road distance is 307.7 miles.
The best way to get from Lake City to Naples without a car is to bus via University which takes 11h 10m and costs $100 - $190.
It takes approximately 11h 10m to get from Lake City to Naples, including transfers.
Lake City to Naples bus services, operated by Greyhound USA, depart from Lake City Bus Station.
Lake City to Naples bus services, operated by Greyhound USA, arrive at Jacksonville station.
Yes, the driving distance between Lake City to Naples is 308 miles. It takes approximately 5h 53m to drive from Lake City to Naples.
Book your Lake City to Naples bus tickets online with Omio.
What companies run services between Lake City, FL, USA and Naples, FL, USA?
You can take a bus from Lake City Bus Station to Naples via Jacksonville, Gainesville, University of South Florida - 3801 USF Holly Dr, and Naples, FL in around 11h 10m.
- Website
- aa.com
Flights from Jacksonville to Miami International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $55–350
Flights from Tallahassee to Miami International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–360
- Website
- flybreeze.com
Flights from Jacksonville to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $120–650
- Website
- jetblue.com
Flights from Jacksonville to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $55–360
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Tallahassee
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Jacksonville
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–18
- Website
- Greyhound
Bus from Lake City Bus Station to Tallahassee
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Gainesville to University of South Florida
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $19–35
- Schedules at
- Flixbus USA
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 2 hours
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- $30–60
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from University of South Florida - 3801 USF Holly Dr to Naples, FL
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- RedCoach
Bus from Fort Lauderdale Airport to Naples, FL
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- RedCoach
Bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Naples, FL
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $110–220
- Website
- RedCoach
Bus from Miami Airport to Naples, FL
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- RedCoach
Bus from Miami Airport to Naples, FL
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- RedCoach
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Lake City to Fort Myers
- Ave. Duration
- 6h 13m
- Frequency
- Once daily
- Estimated price
- $70–90
- Schedules at
- Omnibus Express
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