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How to get fromLake City to San Antonioby bus, plane, bus (Greyhound, Flixbus), train, car, or shuttle

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There are 7 ways to get from Lake City to San Antonio by bus, plane, bus (Greyhound, Flixbus), train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Valdosta, fly to San Antonio International Airport

    best
    1. Take the bus from Lake City Bus Station to Valdostabus bus
    2. Fly from Valdosta (VLD) to San Antonio International Airport (SAT)plane plane VLD - SAT
    7h 35m
    $154–687

  2. Bus

    1. Take the bus from Lake City Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Houston Bus Stationbus bus
    3. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    23h 25m
    $156–300

  3. Bus, train

    1. Take the bus from Lake City Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain train
    29h 30m
    $257–525

  4. Drive 1,005.2 mi

    1. Drive from Lake City to San Antoniocar car 1,005.2 mi
    16h 19m
    $184–265

  5. Bus to Jacksonville, fly to San Antonio International Airport

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to San Antonio International Airport (SAT)plane plane JAX - SAT
    8h 24m
    $512–1,322

  6. Bus to Jacksonville, fly to Austin-Bergstrom International Airport, bus

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Austin-Bergstrom International Airport (AUS)plane plane JAX - AUS
    3. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    9h 13m
    $163–747

  7. Bus, shuttle to Tampa, fly to San Antonio International Airport

    1. Take the bus from Lake City to Wildwoodbus bus
    2. Take a shuttle bus from Brownwood Hotel & Spa to Tampa International Airport - Red Terminalshuttle bus
    3. Fly from Tampa (TPA) to San Antonio International Airport (SAT)plane plane TPA - SAT
    8h 59m
    $364–1,459

Lake City to San Antonio by bus

Calendar14Weekly Buses
Duration23h 25mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from Lake City to San Antonio.ExpandLaunch map view
  • Distance: 986.1 mi
  • Duration: 7h 35m

What companies run services between Lake City, FL, USA and San Antonio, TX, USA?

You can take a bus from Lake City Bus Station to San Antonio Bus Station via Tallahassee and Houston Bus Station in around 23h 25m.

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