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How to get fromLake City to San Diegoby bus, plane, bus (Greyhound, Amtrak), train, car, or shuttle

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There are 8 ways to get from Lake City to San Diego by bus, plane, bus (Greyhound, Amtrak), train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Valdosta, fly

    best
    1. Take the bus from Lake City Bus Station to Valdostabus bus
    2. Fly from Valdosta (VLD) to San Diego International Airport (SAN)plane plane VLD - SAN
    10h 8m
    $202–785

  2. Bus

    1. Take the bus from Lake City Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 11h
    $415–804

  3. Bus, train

    1. Take the bus from Lake City Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Yuma Amtraktrain train
    4. Take the bus from Yuma County Area Transit to El Cajon Transit Centerbus bus
    2d 13h
    $655–1,412

  4. Drive 2,259.7 mi

    1. Drive from Lake City to San Diegocar car 2,259.7 mi
    35h 58m
    $413–596

  5. Bus to Jacksonville, fly

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to San Diego International Airport (SAN)plane plane JAX - SAN
    8h 47m
    $210–870

  6. Bus to Tallahassee, fly

    1. Take the bus from Lake City Bus Station to Tallahasseebus bus
    2. Fly from Tallahassee (TLH) to San Diego International Airport (SAN)plane plane TLH - SAN
    9h 44m
    $230–859

  7. Bus, shuttle to Tampa, fly

    1. Take the bus from Lake City to Wildwoodbus bus
    2. Take a shuttle bus from Brownwood Hotel & Spa to Tampa International Airport - Red Terminalshuttle bus
    3. Fly from Tampa (TPA) to San Diego International Airport (SAN)plane plane TPA - SAN
    10h 28m
    $302–907

  8. Bus, train via Chicago

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d 13h
    $1,230–2,690

Lake City to San Diego by bus and foot

Calendar7Weekly Services
Duration2d 11hAverage Duration
Ticket$415Cheapest Price
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Questions & Answers

Map of how to get from Lake City to San Diego.ExpandLaunch map view
  • Distance: 2,054.9 mi
  • Duration: 10h 8m

What companies run services between Lake City, FL, USA and San Diego, CA, USA?

You can take a bus from Lake City Bus Station to San Diego via Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 11h.

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