There are 2 ways to get from Lake City to Sanibel Island by bus or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Questions & Answers
The cheapest way to get from Lake City to Sanibel Island is to drive which costs $50 - $80 and takes 5h 45m.
The fastest way to get from Lake City to Sanibel Island is to drive which takes 5h 45m and costs $50 - $80.
No, there is no direct bus from Lake City to Sanibel Island. However, there are services departing from Lake City and arriving at Fort Myers via . The journey, including transfers, takes approximately 6h 48m.
The distance between Lake City and Sanibel Island is 349 miles. The road distance is 291.6 miles.
The best way to get from Lake City to Sanibel Island without a car is to bus which takes 6h 48m and costs $140 - $180.
It takes approximately 6h 48m to get from Lake City to Sanibel Island, including transfers.
Lake City to Sanibel Island bus services, operated by Omnibus Express, depart from Lake City station.
Lake City to Sanibel Island bus services, operated by Omnibus Express, arrive at Fort Myers station.
Yes, the driving distance between Lake City to Sanibel Island is 292 miles. It takes approximately 5h 45m to drive from Lake City to Sanibel Island.
There are 3331+ hotels available in Sanibel Island.
What companies run services between Lake City, FL, USA and Sanibel Island, FL, USA?
Omnibus Express operates a bus from Lake City to Fort Myers once daily. Tickets cost $70–90 and the journey takes 6h 13m.
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Lake City to Fort Myers
- Ave. Duration
- 6h 13m
- Frequency
- Once daily
- Estimated price
- $70–90
- Schedules at
- Omnibus Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide


