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How to get fromLake City to South Carolinaby bus, train, car, plane, or taxi

Find Transport to South Carolina

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There are 4 ways to get from Lake City to South Carolina by bus, train, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus Greyhound US0760S
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train Silver Meteor
    7h 23m
    $115–230

  2. Drive 291.6 mi

    cheapest
    1. Drive from Lake City to Charlestoncar car 291.6 mi
    5h 13m
    $54–77

  3. Bus to Jacksonville, fly, taxi

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Charlotte Douglas International Airport (CLT)plane plane JAX - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 29m
    $175–670

  4. Bus to Tallahassee, fly, taxi

    1. Take the bus from Lake City Bus Station to Tallahasseebus bus
    2. Fly from Tallahassee (TLH) to Charlotte Douglas International Airport (CLT)plane plane TLH - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 38m
    $210–709

Jacksonville (JAX) to Charlotte Douglas International Airport (CLT) flights

Calendar41Weekly Planes
Duration1h 27mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Lake City to South Carolina.ExpandLaunch map view
  • Distance: 323.8 mi
  • Duration: 7h 23m

What companies run services between Lake City, FL, USA and South Carolina, USA?

There is no direct connection from Lake City to South Carolina. However, you can take the bus to Jacksonville, walk to JRTC Bay H, take the line 4 bus to Amtrak Station, walk to Jacksonville, take the train to Charleston Amtrak Station, then take the taxi to Charleston. Alternatively, you can drive from Lake City to Charleston in around 5h 13m.

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