Rome2Rio

How to get fromLake City to Tupeloby bus (Greyhound), car, bus, or plane

Find Transport to Tupelo

See all options

There are 5 ways to get from Lake City to Tupelo by bus (Greyhound), car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Lake City Bus Station to Atlanta Bus Stationbus bus Greyhound US0630
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    12h 49m
    $104–189
  2. Bus to Valdosta, fly to Golden Triangle Regional Airport, drive

    cheapest
    1. Take the bus from Lake City Bus Station to Valdostabus bus
    2. Fly from Valdosta (VLD) to Golden Triangle Regional Airport (GTR)plane plane VLD - GTR
    3. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    8h 7m
    $89–383
  3. Drive 495.2 mi

    1. Drive from Lake City to Tupelocar car 495.2 mi
    9h 10m
    $91–131
  4. Bus to Jacksonville, fly to Golden Triangle Regional Airport, drive

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Golden Triangle Regional Airport (GTR)plane plane JAX - GTR
    3. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    8h 1m
    $92–438
  5. Bus to Jacksonville, fly to Tupelo Regional Airport

    1. Take the bus from Lake City Bus Station to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Tupelo Regional Airport (TUP)plane plane JAX - TUP
    7h 32m
    $110–489

Valdosta (VLD) to Golden Triangle Regional Airport (GTR) flights

Calendar21Weekly Planes
Duration7h 35mAverage Duration
Ticket$58Cheapest Price
See schedules

Questions & Answers

What companies run services between Lake City, FL, USA and Tupelo, MS, USA?

You can take a bus from Lake City Bus Station to Tupelo via Atlanta Bus Station and Tupelo in around 12h 49m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers