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How to get fromLake Erie to Kentuckyby bus (Amtrak), car, plane, bus, train, or bus (Greyhound, Amtrak)

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There are 9 ways to get from Lake Erie to Kentucky by bus (Amtrak), car, plane, bus, train, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Cleveland to Toledobus bus
    2. Take the bus from Toledo to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 50m
    $56–159

  2. Drive  530.9 mi

    1. Drive from Buffalo to Louisvillecar car 530.9 mi
    9h 1m
    $97–140

  3. Fly Cleveland-Hopkins International Airport to Nashville, bus

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Nashville (BNA)plane plane CLE - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    8h 15m
    $164–344

  4. Train, bus via Toledo

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    11h 11m
    $74–188

  5. Train, bus

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo Bus Stop to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    11h 26m
    $88–178

  6. Bus via Columbus

    1. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 36m
    $115–322

  7. Train, bus to Detroit, fly to Covington

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo to Dearbornbus bus
    3. Fly from Detroit (DTW) to Covington (CVG)plane plane DTW - CVG
    8h 37m
    $801–1,405

  8. Train, bus to Detroit, fly to Louisville International Airport

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo to Dearbornbus bus
    3. Fly from Detroit (DTW) to Louisville International Airport (SDF)plane plane DTW - SDF
    9h 4m
    $159–853

  9. Train, bus to Detroit, fly to Blue Grass Airport

    1. Take the train from Cleveland Amtrak to Toledotrain train
    2. Take the bus from Toledo to Dearbornbus bus
    3. Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane plane DTW - LEX
    10h 7m
    $115–532

Lake Erie to Kentucky by bus

Calendar7Weekly Buses
Duration10h 50mAverage Duration
Ticket$56Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lake Erie to Kentucky.ExpandLaunch map view
  • Distance: 449.6 mi
  • Duration: 10h 50m

What companies run services between Lake Erie, OH, USA and Kentucky, USA?

You can take a bus from St. Clair Av & W Mall Dr to Louisville, KY via Chester Av & E 15Th St, Cleveland, Toledo, and Indianapolis Union Station in around 10h 50m.

Airlines
Train operators
Bus operators

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