There are 9 ways to get from Lake Forest to Mayo Clinic by train, plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Chicago O'Hare International Airport, fly to Rochester
best- Take the train from Lake Forest. to Clybourntrain
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
5h 39m$49–342Bus
- Take the bus from Metro Train Station - 13th Avenue and 54th Street to Milwaukee Intermodal/Amtrak Stationbus Wisconsin Coach Lines
- Take the bus from Milwaukee to Rochesterbus Jefferson Lines 966
9h 58m$83–123Train, bus via Saint Paul
- Take the train from Lake Forest. to Chicago OTCtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
12h 14m$156–319Drive 314.9 mi
- Drive from Lake Forest to Mayo Cliniccar 314.9 mi
5h 38m$58–83Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from Lake Forest. to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane MDW - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 27m$129–513Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from Lake Forest. to Clybourntrain
- Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane ORD - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 22m$280–514Bus to General Mitchell International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Metro Train Station - 13th Avenue and 54th Street to Mitchell Airportbus
- Fly from General Mitchell International Airport (MKE) to Minneapolis–Saint Paul International Airport (MSP)plane MKE - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 59m$663–1,072Train, bus
- Take the train from Glenview Amtrak Station to Milwaukeetrain Hiawatha Service / ...
- Take the bus from Milwaukee to Rochesterbus Jefferson Lines 966
10h 35m$97–153Bus via Madison
- Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus Van Galder
- Take the bus from Madison to Rochesterbus Jefferson Lines 966
11h 14m$80–137
Lake Forest to Mayo Clinic by train, bus, and foot
Questions & Answers
The cheapest way to get from Lake Forest to Mayo Clinic is to drive which costs $55 - $85 and takes 5h 38m.
The fastest way to get from Lake Forest to Mayo Clinic is to drive which takes 5h 38m and costs $55 - $85.
No, there is no direct bus from Lake Forest station to Mayo Clinic. However, there are services departing from Metro Train Station - 13th Avenue and 54th Street and arriving at Rochester via Milwaukee. The journey, including transfers, takes approximately 9h 58m.
The distance between Lake Forest and Mayo Clinic is 318 miles. The road distance is 316.8 miles.
The best way to get from Lake Forest to Mayo Clinic without a car is to bus which takes 9h 58m and costs $80 - $130.
It takes approximately 5h 39m to get from Lake Forest to Mayo Clinic, including transfers.
Lake Forest to Mayo Clinic bus services, operated by Rockland Coaches, depart from Metro Train Station - 13th Avenue and 54th Street.
Lake Forest to Mayo Clinic bus services, operated by Rockland Coaches, arrive at Milwaukee Intermodal/Amtrak Station.
Yes, the driving distance between Lake Forest to Mayo Clinic is 317 miles. It takes approximately 5h 38m to drive from Lake Forest to Mayo Clinic.
There are 68+ hotels available in Mayo Clinic.
What companies run services between Lake Forest, IL, USA and Mayo Clinic, MN, USA?
You can take a train from Lake Forest. to Mayo Clinic via Kenosha, Metro Train Station - 13th Avenue and 54th Street, Milwaukee Intermodal/Amtrak Station, Milwaukee, and Rochester in around 9h 58m.
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $50–320
Flights from Chicago Midway International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–450
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $55–370
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $80–550
- Website
- southwest.com
Flights from Chicago Midway International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $70–450
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $40–290
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $55–370
- Website
- united.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–290
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $55–370
- Website
- suncountry.com
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 36m
- When
- Sunday, Monday, and Thursday
- Estimated price
- $55–370
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 19m
- When
- Sunday
- Estimated price
- $80–550
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Lake Forest. to Clybourn
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Train from Lake Forest. to Chicago OTC
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- $5–6
- Website
- Metra
- Adult
- $5–6
Train from Lake Forest. to Chicago OTC
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- $5–6
- Website
- Metra
- Adult
- $5–6
Train from Lake Forest. to Clybourn
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Metra
- Adult
- $4–6
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $120–270
- Website
- Amtrak
Train from Glenview Amtrak Station to Milwaukee
- Ave. Duration
- 1h 7m
- Frequency
- Every 4 hours
- Estimated price
- $21–45
- Website
- Amtrak
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from Metro Train Station - 13th Avenue and 54th Street to Milwaukee Intermodal/Amtrak Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $8–17
- Schedules at
- Rockland Coaches
- Adult
- $8–17
Bus from Metro Train Station - 13th Avenue and 54th Street to Mitchell Airport
- Ave. Duration
- 1h 7m
- Frequency
- Every 4 hours
- Estimated price
- $6–14
- Schedules at
- Rockland Coaches
- Adult
- $6–14
Bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide









