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How to get fromLake Mary to Chicagoby plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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There are 7 ways to get from Lake Mary to Chicago by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Chicago Midway International Airport

    best
    1. Fly from Orlando (MCO) to Chicago Midway International Airport (MDW)plane plane MCO - MDW
    5h 44m
    $207–491
  2. Fly Orlando to Chicago O'Hare International Airport

    cheapest
    1. Fly from Orlando (MCO) to Chicago O'Hare International Airport (ORD)plane plane MCO - ORD
    6h 8m
    $77–611
  3. Bus

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    26h 29m
    $180–355
  4. Train (Amtrak)

    1. Take the train from Deland to Chicago Union Stationtrain train Floridian
    39h 23m
    $553–1,104
  5. Drive 1,103.8 mi

    1. Drive from Lake Mary to Chicagocar car 1,103.8 mi
    20h 5m
    $202–291
  6. Fly Orlando Sanford to South Bend, train

    1. Fly from Orlando Sanford (SFB) to South Bend (SBN)plane plane SFB - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    5h 41m
    $156–731
  7. Fly Orlando to General Mitchell International Airport, train

    1. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 8m
    $205–680

Lake Mary to Chicago by train and bus

Calendar40Weekly Services
Duration26h 29mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

What companies run services between Lake Mary, FL, USA and Chicago, IL, USA?

Southwest Airlines flies from Orlando (MCO) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a train from Lake Mary to Chicago Bus Station via LYNX Central, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Atlanta Bus Station in around 26h 29m.

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