There are 9 ways to get from Lake Mary to Panama City Beach by plane, bus (Flixbus, Greyhound), car, bus, bus (Greyhound), bus (Greyhound, Flixbus), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Northwest Florida Beaches International Airport
best- Fly from Orlando (MCO) to Northwest Florida Beaches International Airport (ECP)plane MCO - ECP
6h 22m$120–411Drive 341.2 mi
cheapest- Drive from Lake Mary to Panama City Beachcar 341.2 mi
6h 59m$63–90Bus via Gainesville
- Take the bus from Orlando Bus Station to Gainesvillebus
- Take the bus from Gainesville to Tallahasseebus
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus
11h 3m$69–116Fly Orlando to Destin–Fort Walton Beach Airport, drive
- Fly from Orlando (MCO) to Destin–Fort Walton Beach Airport (VPS)plane MCO - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar
7h 35m$80–372Fly Orlando to Pensacola International Airport, bus
- Fly from Orlando (MCO) to Pensacola International Airport (PNS)plane MCO - PNS
- Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus
7h 17m$109–797Fly Daytona Beach International Airport to Northwest Florida Beaches International Airport
- Fly from Daytona Beach International Airport (DAB) to Northwest Florida Beaches International Airport (ECP)plane DAB - ECP
8h 23m$152–623Bus
- Take the bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus Miami
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus Greyhound US0799 / ...
11h 6m$96–180Bus #2
- Take the bus from Orlando Bus Station to Tallahasseebus Greyhound US0761S
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus Greyhound US0799 / ...
11h 53m$69–122Train, bus
- Take the train from Deland to Jacksonvilletrain
- Take the bus from Jacksonville to Tallahasseebus
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus
11h 57m$88–174
Orlando (MCO) to Northwest Florida Beaches International Airport (ECP) flights
Questions & Answers
The cheapest way to get from Lake Mary to Panama City Beach is to drive which costs $60 - $90 and takes 6h 59m.
The fastest way to get from Lake Mary to Panama City Beach is to fly which takes 6h 22m and costs $120 - $420.
No, there is no direct bus from Lake Mary to Panama City Beach station. However, there are services departing from N Garland Ave & W Amelia St and arriving at Panama City Beach Bus Station via Orlando Bus Station, Gainesville and Tallahassee. The journey, including transfers, takes approximately 11h 3m.
The distance between Lake Mary and Panama City Beach is 363 miles. The road distance is 343.2 miles.
The best way to get from Lake Mary to Panama City Beach without a car is to bus via Gainesville which takes 11h 3m and costs $65 - $120.
It takes approximately 6h 22m to get from Lake Mary to Panama City Beach, including transfers.
Lake Mary to Panama City Beach bus services, operated by Flixbus USA, depart from Orlando Bus Station.
The best way to get from Lake Mary to Panama City Beach is to fly which takes 6h 22m and costs $120 - $420. Alternatively, you can bus via Gainesville, which costs $65 - $120 and takes 11h 3m.
Lake Mary to Panama City Beach bus services, operated by Flixbus USA, arrive at Gainesville station.
Panama City Beach is 1h behind Lake Mary. It is currently 1:23 PM in Lake Mary and 12:23 PM in Panama City Beach.
What companies run services between Lake Mary, FL, USA and Panama City Beach, FL, USA?
Delta, Southwest Airlines, and two other airlines fly from Orlando (MCO) to Northwest Florida Beaches International Airport (ECP) hourly. Alternatively, you can take a train from Lake Mary to Panama City Beach via LYNX Central, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Gainesville, Tallahassee, and Panama City Beach Bus Station in around 11h 3m.
- Website
- delta.com
Flights from Orlando to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $65–340
Flights from Orlando to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $65–350
Flights from Orlando to Pensacola International Airport via Atlanta
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $60–310
Flights from Daytona Beach International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $95–550
- Website
- southwest.com
Flights from Orlando to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 4h 38m
- When
- Sunday, Saturday, Monday, Thursday, and Friday
- Estimated price
- $85–410
Flights from Orlando to Northwest Florida Beaches International Airport via St. Louis
- Ave. Duration
- 6h 19m
- When
- Sunday and Saturday
- Estimated price
- $110–500
Flights from Orlando to Northwest Florida Beaches International Airport via Houston Hobby Apt
- Ave. Duration
- 6h 15m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–490
Flights from Orlando to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 4h 41m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $85–410
- Website
- aa.com
Flights from Orlando to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $80–390
Flights from Orlando to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $80–400
Flights from Orlando to Destin–Fort Walton Beach Airport via Miami
- Ave. Duration
- 6h 15m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–350
Flights from Daytona Beach International Airport to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Orlando to Pensacola International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $80–750
- Website
- united.com
Flights from Orlando to Northwest Florida Beaches International Airport via Houston
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $110–490
- Website
- flyfrontier.com
Flights from Orlando to Pensacola International Airport
- Ave. Duration
- 1h 33m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $80–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Deland to Jacksonville
- Ave. Duration
- 2h 11m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Orlando Bus Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $17–29
- Schedules at
- Flixbus USA
Bus from Gainesville to Tallahassee
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Tallahassee
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $40–70
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Pensacola Airport to Panama City Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Orlando Bus Station to Tallahassee
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $40–75
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Jacksonville to Tallahassee
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $25–50
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Field
- Ave. Duration
- 4h 55m
- Frequency
- 3 times a day
- Estimated price
- $65–130
- Website
- RedCoach
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More Questions & Answers
Yes, the driving distance between Lake Mary to Panama City Beach is 343 miles. It takes approximately 6h 59m to drive from Lake Mary to Panama City Beach.
There are 4456+ hotels available in Panama City Beach.










