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How to get fromLake Mary to South Carolinaby plane, taxi, train (Amtrak), car, or train

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There are 7 ways to get from Lake Mary to South Carolina by plane, taxi, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando Sanford to Asheville Regional Airport, taxi

    best
    1. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    2h 49m
    $208–526

  2. Drive 362 mi

    cheapest
    1. Drive from Lake Mary to Charlestoncar car 362 mi
    6h 16m
    $67–96

  3. Train (Amtrak)

    1. Take the train from Deland to Charleston Amtrak Stationtrain train Silver Meteor
    8h 25m
    $143–284

  4. Train to Orlando, fly to Charlotte Douglas International Airport, taxi

    1. Take the train from Lake Mary to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 40m
    $185–446

  5. Fly Orlando Sanford to Greenville–Spartanburg International Airport

    1. Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane plane SFB - GSP
    1h 58m
    $128–551

  6. Train to Orlando, fly to Charleston International Airport

    1. Take the train from Lake Mary to Sand Lake Roadtrain train
    2. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    4h 49m
    $72–258

  7. Fly Orlando Sanford to Concord, taxi

    1. Fly from Orlando Sanford (SFB) to Concord (USA)plane plane SFB - USA
    2. Take the taxi from Concord (USA) to Rock Hilltaxi taxi
    2h 41m
    $202–386

Orlando Sanford (SFB) to Asheville Regional Airport (AVL) flights

Calendar11Weekly Planes
Duration1h 39mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Lake Mary to South Carolina.ExpandLaunch map view
  • Distance: 521.4 mi
  • Duration: 2h 49m

What companies run services between Lake Mary, FL, USA and South Carolina, USA?

Amtrak operates a train from Deland to Charleston Amtrak Station once daily. Tickets cost $110–240 and the journey takes 6h 45m. Alternatively, Allegiant Air flies from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP) twice a week.

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