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How to get fromLake Michigan to Louisvilleby subway, plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Amtrak)

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There are 7 ways to get from Lake Michigan to Louisville by subway, plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Chicago Midway International Airport, fly to Louisville International Airport

    best
    1. Take the subway from Roosevelt to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    3h 53m
    $98–658

  2. Bus (Amtrak)

    cheapest
    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    7h 53m
    $52–62

  3. Bus via Indianapolis

    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    7h 11m
    $54–98

  4. Train, bus (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    8h 57m
    $124–218

  5. Drive  293.6 mi

    1. Drive from Chicago to Louisvillecar car 293.6 mi
    5h 4m
    $54–78

  6. Fly Chicago O'Hare International Airport to Louisville International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 25m
    $74–468

  7. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 36m
    $56–304

Lake Michigan to Louisville by bus

Calendar14Weekly Buses
Duration7h 11mAverage Duration
Ticket$54Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lake Michigan to Louisville.ExpandLaunch map view
  • Distance: 286.8 mi
  • Duration: 3h 53m

What companies run services between Lake Michigan, MI, USA and Louisville, KY, USA?

You can take a bus from Michigan & Washington to Louisville, KY via Harrison & Jefferson, Chicago Bus Station, and Indianapolis Union Station in around 7h 11m. Alternatively, American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) every 3 hours.

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Need to know: Greyhound

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