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How to get fromLake Saint Louis to Indianapolisby bus (Greyhound), car, taxi, plane, or bus (Flixbus)

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There are 4 ways to get from Lake Saint Louis to Indianapolis by bus (Greyhound), car, taxi, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    7h 2m
    $72–113

  2. Drive 273.5 mi

    cheapest
    1. Drive from Lake Saint Louis to Indianapoliscar car 273.5 mi
    4h 40m
    $50–73

  3. Taxi, fly

    1. Take the taxi from Lake Saint Louis to St-Louis-Airport-STLtaxi taxi
    2. Fly from Lambert–St. Louis International Airport (STL) to Indianapolis (IND)plane plane STL - IND
    4h 59m
    $169–681

  4. Bus via Champaign

    1. Take the bus from St Louis Bus Station to Champaign Intermodal Trans Ctrbus bus FlixBus N2521 / ...
    2. Take the bus from Champaign to Indianapolisbus bus Btw 1402
    9h 2m

Lambert–St. Louis International Airport (STL) to Indianapolis (IND) flights

Calendar123Weekly Planes
Duration4h 12mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Lake Saint Louis to Indianapolis.ExpandLaunch map view
  • Distance: 283.4 mi
  • Duration: 7h 2m

What companies run services between Lake Saint Louis, MO, USA and Indianapolis, IN, USA?

Greyhound-us operates a bus from St Louis Bus Station to Indianapolis Union Station 3 times a day, and the journey takes 4h 25m. Greyhound USA also services this route 3 times a day.

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