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How to get fromLake Zurich to St. Louisby train (Amtrak), bus (Flixbus), car, train, plane, subway, or bus

Find Transport to St. Louis

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There are 6 ways to get from Lake Zurich to St. Louis by train (Amtrak), bus (Flixbus), car, train, plane, subway, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Barrington to Chicago OTCtrain train Up-Nw
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    7h 4m
    $98–213

  2. Drive  307.4 mi

    cheapest
    1. Drive from Lake Zurich to St. Louiscar car 307.4 mi
    5h 13m
    $57–81

  3. Bus

    1. Take the bus from Woodfield Mall to Illinois Terminalbus bus Chicago to Champaign via shopping SB / ...
    2. Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus Stationbus bus FlixBus N2521 / ...
    7h 55m
    $114–155

  4. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Barrington to Irving Parktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 23m
    $349–737

  5. Train, subway to Chicago Midway International Airport, fly

    1. Take the train from Barrington to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    5h 4m
    $100–538

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airportbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    6h 7m
    $543–922

Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) flights

Calendar104Weekly Planes
Duration1h 28mAverage Duration
Ticket$52Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lake Zurich to St. Louis.ExpandLaunch map view
  • Distance: 318.2 mi
  • Duration: 7h 4m

What companies run services between Lake Zurich, IL, USA and St. Louis, MO, USA?

You can take a vehicle from Lake Zurich to St. Louis via Barrington, Chicago OTC, Madison & Canal, Clinton & Jackson, and Chicago Union Station in around 7h 4m. Alternatively, you can take a vehicle from Lake Zurich to St Louis Bus Station via Woodfield Mall, Illinois Terminal, and Champaign Intermodal Trans Ctr in around 7h 55m.

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