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How to get fromLakeland to Des Moinesby car, plane, bus (Amtrak, Flixbus, Greyhound), train, or bus

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There are 7 ways to get from Lakeland to Des Moines by car, plane, bus (Amtrak, Flixbus, Greyhound), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly

    best
    1. Drive from Lakeland to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    4h 38m
    $131–531

  2. Train to Orlando, fly

    cheapest
    1. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    8h 12m
    $127–512

  3. Amtrak Thruway, bus

    1. Take the bus from Lakeland to Tampa Union Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    34h 2m
    $233–407

  4. Train, bus

    1. Take the train from Lakeland Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    47h 59m
    $519–1,116

  5. Drive  1,329.3 mi

    1. Drive from Lakeland to Des Moinescar car 1,329.3 mi
    23h 14m
    $243–351

  6. Amtrak Thruway to Tampa, fly

    1. Take the bus from Lakeland to Tampa Union Stationbus bus
    2. Fly from Tampa (TPA) to Des Moines (DSM)plane plane TPA - DSM
    7h 57m
    $132–531

  7. Amtrak Thruway to Saint Petersburg–Clearwater International Airport, fly

    1. Take the bus from Lakeland to St. Petersburgbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Des Moines (DSM)plane plane PIE - DSM
    6h 29m
    $137–537

Lakeland to Des Moines by bus

Calendar7Weekly Buses
Duration34h 2mAverage Duration
Ticket$233Cheapest Price
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Questions & Answers

Map of how to get from Lakeland to Des Moines.ExpandLaunch map view
  • Distance: 1,204.7 mi
  • Duration: 4h 38m

What companies run services between Lakeland, FL, USA and Des Moines, IA, USA?

You can take a bus from Lakeland to Des Moines via Tampa Union Station, Nebraska Ave @ Twiggs St, Tampa Bus Station, Atlanta Bus Station, and Indianapolis Union Station in around 34h 2m.

Airlines
Train operators
Bus operators

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