There are 11 ways to get from Lakeland to Florence by train (Amtrak), bus (Greyhound, Flixbus), car, bus, plane, train, or bus (Amtrak, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain Floridian
- Take the train from Kissimmee Amtrak Station to Florence Stationtrain Silver Meteor
12h 7m$174–368Drive 488.4 mi
cheapest- Drive from Lakeland to Florencecar 488.4 mi
8h 34m$90–129Bus
- Take the bus from Winter Haven Transportation Center to Orlando Bus Stationbus Greyhound US0770S
- Take the bus from Orlando Bus Station to Florencebus FlixBus N2472
12h 23m$92–162Amtrak Thruway to Tampa, fly to Charleston International Airport, train
- Take the bus from Lakeland to Tampa Union Stationbus
- Fly from Tampa (TPA) to Charleston International Airport (CHS)plane TPA - CHS
- Take the train from Charleston Amtrak Station to Florence Stationtrain
9h 19m$191–432Bus via Jacksonville
- Take the bus from Lakeland to Jacksonvillebus
- Take the bus from Jacksonville to Sumter Bus Stopbus
- Take the bus from Sumter Bus Stop to Florence Bus Stationbus
15h 49m$121–202Amtrak Thruway to Tampa, fly to Charlotte Douglas International Airport, bus
- Take the bus from Lakeland to Tampa Union Stationbus
- Fly from Tampa (TPA) to Charlotte Douglas International Airport (CLT)plane TPA - CLT
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
10h 15m$134–616Train to Orlando, fly to Charleston International Airport, train
- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain
- Fly from Orlando (MCO) to Charleston International Airport (CHS)plane MCO - CHS
- Take the train from Charleston Amtrak Station to Florence Stationtrain
9h 29m$117–353Train to Orlando, fly to Charlotte Douglas International Airport, bus
- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain
- Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane MCO - CLT
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
10h 27m$140–417Amtrak Thruway to Tampa, fly to Myrtle Beach, bus, train
- Take the bus from Lakeland to Tampa Union Stationbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Florence Stationtrain
10h 43m$148–391Fly Lakeland to Concord, bus
- Fly from Lakeland (LAL) to Concord (USA)plane LAL - USA
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
7h 55m$154–268Train to Orlando, fly to Myrtle Beach, bus, train
- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain
- Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Florence Stationtrain
10h 51m$164–462
Lakeland to Florence by train (Amtrak)
Questions & Answers
The cheapest way to get from Lakeland to Florence is to drive which costs $85 - $130 and takes 8h 34m.
The fastest way to get from Lakeland to Florence is to fly and bus which takes 7h 55m and costs $150 - $270.
No, there is no direct bus from Lakeland to Florence. However, there are services departing from Park & Ride at Rose St. and arriving at Florence via Winter Haven Transportation Center and Orlando Bus Station. The journey, including transfers, takes approximately 12h 23m.
No, there is no direct train from Lakeland station to Florence station. However, there are services departing from Lakeland Amtrak Station and arriving at Florence Station via Kissimmee Amtrak Station. The journey, including transfers, takes approximately 12h 7m.
The distance between Lakeland and Florence is 553 miles. The road distance is 491.2 miles.
The best way to get from Lakeland to Florence without a car is to train which takes 12h 7m and costs $170 - $370.
It takes approximately 12h 7m to get from Lakeland to Florence, including transfers.
Lakeland to Florence bus services, operated by Greyhound USA, depart from Winter Haven Transportation Center station.
Lakeland to Florence train services, operated by Amtrak, depart from Lakeland Amtrak Station.
The best way to get from Lakeland to Florence is to train which takes 12h 7m and costs $170 - $370. Alternatively, you can bus, which costs $90 - $170 and takes 12h 23m.
What companies run services between Lakeland, FL, USA and Florence, SC, USA?
You can take a train from Lakeland Amtrak Station to Florence Station via Kissimmee Amtrak Station in around 12h 7m. Alternatively, you can take a bus from Park & Ride at Rose St. to Florence via Winter Haven Transportation Center, Orlando Bus Station, and Florence in around 12h 23m.
- Website
- aa.com
Flights from Tampa to Charleston International Airport via Miami
- Ave. Duration
- 3h 57m
- When
- Tuesday
- Estimated price
- $80–420
Flights from Tampa to Charlotte Douglas International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $95–550
Flights from Orlando to Charlotte Douglas International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $80–460
Flights from Tampa to Myrtle Beach via Charlotte Douglas International Airport
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $65–350
Flights from Orlando to Myrtle Beach via Charlotte Douglas International Airport
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $55–300
- Website
- delta.com
Flights from Tampa to Charleston International Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $80–420
Flights from Tampa to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $110–600
Flights from Orlando to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $95–500
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $70–360
Flights from Orlando to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–310
- Website
- flybreeze.com
Flights from Tampa to Charleston International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $140–340
Flights from Orlando to Charleston International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–250
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 41m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–260
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–280
- Website
- flyfrontier.com
Flights from Orlando to Charlotte Douglas International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $100–340
- Website
- aveloair.com
Flights from Lakeland to Concord
- Ave. Duration
- 1h 41m
- When
- Thursday and Sunday
- Estimated price
- $75–150
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $13–29
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Florence Station
- Ave. Duration
- 10h 25m
- Frequency
- Once daily
- Estimated price
- $160–340
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Florence Station
- Ave. Duration
- 1h 34m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $13–29
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Florence Station
- Ave. Duration
- 1h 34m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $13–29
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Florence Station
- Ave. Duration
- 1h 34m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $13–29
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Florence Station
- Ave. Duration
- 1h 34m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Winter Haven Transportation Center to Orlando Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $6–13
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Florence Bus Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando Bus Station to Florence
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a week
- Estimated price
- $70–130
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Lakeland to Tampa Union Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $11–16
- Website
- https://www.amtrak.com/home.html
Bus from Lakeland to Jacksonville
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- https://www.amtrak.com/home.html
Bus from Lakeland to Tampa Union Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $11–16
- Website
- https://www.amtrak.com/home.html
Bus from Lakeland to Tampa Union Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $11–16
- Website
- https://www.amtrak.com/home.html
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More Questions & Answers
Lakeland to Florence bus services, operated by Greyhound USA, arrive at Orlando Bus Station.
Lakeland to Florence train services, operated by Amtrak, arrive at Kissimmee Amtrak Station.
Yes, the driving distance between Lakeland to Florence is 491 miles. It takes approximately 8h 34m to drive from Lakeland to Florence.
Book your Lakeland to Florence train tickets online with Omio.
Book your Lakeland to Florence bus tickets online with Omio.
There are 49+ hotels available in Florence.






