There are 10 ways to get from Lakeland to Florida Keys by train, bus, shuttle, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Lakeland to Hollywood Amtrak Stationtrain Floridian
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
11h 44m$83–174Bus (Greyhound)
cheapest- Take the bus from Winter Haven Transportation Center to Miami Airport Stationbus Greyhound US0740s
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
14h 22m$56–110Amtrak Thruway, bus, shuttle
- Take the bus from Lakeland to Sarasota Amtrak Bus Stopbus
- Take the bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airportbus
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
13h 45m$233–336Drive 349 mi
- Drive from Lakeland to Florida Keyscar 349 mi
7h 9m$64–92Amtrak Thruway, bus to Tampa, fly to Key West International Airport, bus
- Take the bus from Lakeland to Tampa Union Stationbus
- Take the bus from Marion Transit Center to Airport Rental Car Centerbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
7h 8m$159–505Amtrak Thruway to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport
- Take the bus from Lakeland to St. Petersburgbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
7h 23m$129–361Train, train to Orlando, fly to Key West International Airport, bus
- Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee to Sand Lake Roadtrain
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
7h 22m$163–776Drive to Orlando Sanford, fly to Key West International Airport
- Drive from Lakeland to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
5h 44m$126–354Amtrak Thruway to Tampa, fly to Miami International Airport, shuttle
- Take the bus from Lakeland to Tampa Union Stationbus
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 41m$819–1,305Amtrak Thruway to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Lakeland to Tampa Union Stationbus
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 7m$289–725
Lakeland to Florida Keys by train, bus, and foot
Questions & Answers
The cheapest way to get from Lakeland to Florida Keys is to bus which costs $55 - $110 and takes 14h 22m.
The fastest way to get from Lakeland to Florida Keys is to drive and fly which takes 5h 44m and costs $120 - $360.
No, there is no direct bus from Lakeland to Florida Keys. However, there are services departing from Park & Ride at Rose St. and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Winter Haven Transportation Center, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 14h 22m.
The distance between Lakeland and Florida Keys is 370 miles. The road distance is 351.1 miles.
The best way to get from Lakeland to Florida Keys without a car is to train and bus which takes 11h 44m and costs $80 - $180.
It takes approximately 11h 44m to get from Lakeland to Florida Keys, including transfers.
Lakeland to Florida Keys bus services, operated by Greyhound USA, depart from Winter Haven Transportation Center station.
Lakeland to Florida Keys bus services, operated by Greyhound USA, arrive at Miami Airport Station.
Yes, the driving distance between Lakeland to Florida Keys is 351 miles. It takes approximately 7h 9m to drive from Lakeland to Florida Keys.
There are 975+ hotels available in Florida Keys.
What companies run services between Lakeland, FL, USA and Florida Keys, FL, USA?
You can take a bus from Park & Ride at Rose St. to Florida Keys via Winter Haven Transportation Center, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 14h 22m.
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $65–390
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 19m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–650
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $100–470
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- $35–230
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $40–300
- Website
- allegiantair.com
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 3m
- When
- Friday, Wednesday, Saturday, Monday, Thursday, and Sunday
- Estimated price
- $30–240
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Thursday and Sunday
- Estimated price
- $35–240
- Website
- southwest.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $40–300
- Website
- jetblue.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- $40–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Lakeland to Hollywood Amtrak Station
- Ave. Duration
- 4h 27m
- Frequency
- Once daily
- Estimated price
- $60–130
- Website
- Amtrak
Train from Lakeland Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $12–27
- Website
- Amtrak
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from Kissimmee to Sand Lake Road
- Ave. Duration
- 18 min
- Frequency
- Hourly
- Estimated price
- $2–4
- Website
- SunRail
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
Bus from Winter Haven Transportation Center to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Lakeland to Sarasota Amtrak Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
Bus from Lakeland to Tampa Union Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Lakeland to St. Petersburg
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $15–22
- Website
- Amtrak
Bus from Lakeland to Tampa Union Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Lakeland to Tampa Union Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $10–15
- Website
- Amtrak
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Bradenton/Sarasota - Mobil Gas Station to Miami Airport
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- RedCoach
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1 813-254-4278
- Website
- HART
Bus from Marion Transit Center to Airport Rental Car Center
- Ave. Duration
- 32 min
- Frequency
- Every 30 minutes
- Estimated price
- $1–2
- Website
- HART
- Phone
- +1 727-540-1900
- [email protected]
- Website
- Pinellas Suncoast Transit Authority
Bus from Marion Transit Center to Airport Rental Car Center
- Ave. Duration
- 18 min
- Frequency
- Every 3 hours
- Estimated price
- $3
- Schedules at
- Pinellas Suncoast Transit Authority
- Adult
- $3
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide













