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How to get fromLakeland to St. Louisby bus, plane, bus (Amtrak, Flixbus, Greyhound), train (Amtrak), car, or train

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There are 7 ways to get from Lakeland to St. Louis by bus, plane, bus (Amtrak, Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Amtrak Thruway to Tampa, fly

    best
    1. Take the bus from Lakeland to Tampa Union Stationbus bus
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    6h 10m

  2. Drive  999.1 mi

    cheapest
    1. Drive from Lakeland to St. Louiscar car 999.1 mi
    16h 41m
    $177–255

  3. Amtrak Thruway, bus

    1. Take the bus from Lakeland to Tampa Union Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    24h 7m

  4. Train (Amtrak)

    1. Take the train from Lakeland Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    46h 6m
    $1,123–1,733

  5. Train to Orlando, fly

    1. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    6h 33m
    $211–285

  6. Amtrak Thruway to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Lakeland to Sarasota Amtrak Bus Stopbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    8h 13m

  7. Bus

    1. Take the bus from Lakeland to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    27h 4m

Tampa (TPA) to Lambert–St. Louis International Airport (STL) flights

Calendar75Weekly Planes
Duration3h 54mAverage Duration
Ticket$108Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lakeland to St. Louis.ExpandLaunch map view
  • Distance: 927.8 mi
  • Duration: 6h 10m

What companies run services between Lakeland, FL, USA and St. Louis, MO, USA?

You can take a bus from Lakeland to St Louis Bus Station via Tampa Union Station, Nebraska Ave @ Twiggs St, Tampa Bus Station, and Atlanta Bus Station in around 24h 7m. Alternatively, you can take a train from Lakeland Amtrak Station to St. Louis via Chicago Union Station in around 46h 6m.

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