Rome2Rio

How to get fromLancaster to Knoxvilleby train, plane, bus, bus (Greyhound, Flixbus), or car

Find Transport to Knoxville

See all options

There are 11 ways to get from Lancaster to Knoxville by train, plane, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Burbank Bob Hope Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Lancaster to Burbank - Downtowntrain train
    2. Fly from Burbank Bob Hope Airport (BUR) to Mcghee Tyson Airport (TYS)plane plane BUR - TYS
    9h 41m
    $337–1,186

  2. Train to Long Beach Airport, fly to Nashville, drive

    cheapest
    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Fly from Long Beach Airport (LGB) to Nashville (BNA)plane plane LGB - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    12h 16m
    $207–771

  3. Train, bus via Chicago

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Take the train from Los Angeles to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus
    3d 6h
    $1,034–2,008

  4. Bus

    1. Take the bus from MetroLink/Sierra Hwy. to Bakersfield Amtrakbus bus
    2. Take the bus from Bakersfield Train Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    5. Take the bus from New York to Knoxvillebus bus
    3d 14h
    $632–1,143

  5. Drive 2,140.6 mi

    1. Drive from Lancaster to Knoxvillecar car 2,140.6 mi
    34h 19m
    $391–565

  6. Train to Los Angeles International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Mcghee Tyson Airport (TYS)plane plane LAX - TYS
    10h 40m
    $333–1,198

  7. Train to Long Beach Airport, fly to Mcghee Tyson Airport

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Fly from Long Beach Airport (LGB) to Mcghee Tyson Airport (TYS)plane plane LGB - TYS
    11h 44m
    $352–1,291

  8. Train, train to Ontario International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Take the train from L.A. Union Station to Rancho Cucamongatrain train
    3. Fly from Ontario International Airport (ONT) to Mcghee Tyson Airport (TYS)plane plane ONT - TYS
    12h 33m
    $361–1,291

  9. Train to Los Angeles International Airport, fly to Nashville, drive

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Nashville (BNA)plane plane LAX - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    10h 51m
    $238–398

  10. Train to John Wayne Airport Orange County, fly to Mcghee Tyson Airport

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Fly from John Wayne Airport Orange County (SNA) to Mcghee Tyson Airport (TYS)plane plane SNA - TYS
    13h 36m
    $361–1,292

  11. Train, bus

    1. Take the train from Lancaster to L.A. Union Stationtrain train
    2. Take the train from Los Angeles to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus
    3d 9h
    $1,194–2,418

Burbank Bob Hope Airport (BUR) to Mcghee Tyson Airport (TYS) flights

Calendar40Weekly Planes
Duration6h 52mAverage Duration
Ticket$272Cheapest Price
See schedules

Questions & Answers

Map of how to get from Lancaster to Knoxville.ExpandLaunch map view
  • Distance: 2,020.6 mi
  • Duration: 9h 41m

What companies run services between Lancaster, CA, USA and Knoxville, TN, USA?

You can take a bus from MetroLink/Sierra Hwy. to Knoxville via Bakersfield Amtrak, Bakersfield Train Station, Los Angeles Union Station, St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 3d 14h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers