There are 9 ways to get from Lancaster to Pittsburgh by taxi, plane, bus, train (Amtrak), car, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Manchester Airport, fly
best- Take the taxi from Lancaster to Manchester-Airport-MHTtaxi
- Fly from Manchester Airport (MHT) to Pittsburgh International Airport (PIT)plane MHT - PIT
6h 11m$349–802Drive 547.2 mi
cheapest- Drive from Lancaster to Pittsburghcar 547.2 mi
10h 10m$91–131Bus via Central Hub
- Take the bus from Worcester to New Yorkbus Ppb 5725 / ...
- Take the bus from Port Authority Bus Terminal to Pittsburgh Greyhoundbus New York / ...
14h 1m$118–179Train
- Take the train from Shirley to Portertrain
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Stationtrain
16h 30m$327–1,169Fly from Worcester Regional Airport
- Fly from Worcester Regional Airport (ORH) to Pittsburgh International Airport (PIT)plane ORH - PIT
6h 33m$140–541Train to Boston Logan Airport, fly, bus
- Take the train from Shirley to North Stationtrain
- Fly from Boston Logan Airport (BOS) to Pittsburgh International Airport (PIT)plane BOS - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
6h 30mTaxi, bus to Bradley International Airport, fly, bus
- Take the taxi from Lancaster to Worcestertaxi
- Take the bus from Worcester to Hartfordbus
- Fly from Bradley International Airport (BDL) to Pittsburgh International Airport (PIT)plane BDL - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
6h 39mTrain, train to Theodore Francis Green State Airport, fly
- Take the train from Shirley to Portertrain
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Pittsburgh International Airport (PIT)plane PVD - PIT
8h 29m$136–615Bus (Greyhound)
- Take the bus from Ayer MA to Port Authority Bus Terminalbus Greyhound US0256S
- Take the bus from Port Authority Bus Terminal to Pittsburgh Intermodal Stationbus Greyhound US0410 / ...
16h 20m$146–218
Manchester Airport (MHT) to Pittsburgh International Airport (PIT) flights
Comparing Your Travel Options
The cheapest way to get from Lancaster to Pittsburgh is to drive which costs $90 - $130 and takes 10h 10m.
The fastest way to get from Lancaster to Pittsburgh is to taxi and fly which takes 6h 11m and costs $340 - $800.
No, there is no direct bus from Lancaster to Pittsburgh. However, there are services departing from West Boylston WalMart and arriving at Pittsburgh Greyhound via Worcester and Port Authority Bus Terminal. The journey, including transfers, takes approximately 14h 1m.
No, there is no direct train from Lancaster to Pittsburgh station. However, there are services departing from Shirley and arriving at Pittsburgh Amtrak Station via Porter, Boston and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 16h 30m.
The distance between Lancaster and Pittsburgh is 555 miles. The road distance is 550.4 miles.
The best way to get from Lancaster to Pittsburgh without a car is to bus via Central Hub which takes 14h 1m and costs $110 - $180.
It takes approximately 6h 11m to get from Lancaster to Pittsburgh, including transfers.
Lancaster to Pittsburgh bus services, operated by Peter Pan Bus Lines, depart from Worcester station.
Lancaster to Pittsburgh train services, operated by MBTA, depart from Shirley station.
The best way to get from Lancaster to Pittsburgh is to bus via Central Hub which takes 14h 1m and costs $110 - $180. Alternatively, you can train, which costs $320 - $1,200 and takes 16h 30m, you could also fly, which costs $140 - $550 and takes 6h 33m.
What companies run services between Lancaster, MA, USA and Pittsburgh, PA, USA?
You can take a vehicle from Lancaster to Pittsburgh Greyhound via West Boylston WalMart, Central Hub, Worcester, New York, and Port Authority Bus Terminal in around 14h 1m. Alternatively, you can take a vehicle from Lancaster to Pittsburgh Amtrak Station via Shirley, Porter, Porter, South Station, Boston, and Ny Moynihan Train Hall At Penn Station in around 16h 30m.
- Website
- united.com
Flights from Manchester Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–500
Flights from Boston Logan Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $100–600
Flights from Bradley International Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $90–550
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $95–550
- Website
- aa.com
Flights from Manchester Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $90–500
Flights from Manchester Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 48m
- When
- Saturday
- Estimated price
- $85–490
Flights from Manchester Airport to Pittsburgh International Airport via Charlotte
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 3h 48m
- When
- Monday to Friday
- Estimated price
- $95–600
Flights from Bradley International Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $90–550
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 9m
- When
- Saturday
- Estimated price
- $95–550
- Website
- southwest.com
Flights from Manchester Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 53m
- When
- Monday to Thursday
- Estimated price
- $85–500
Flights from Manchester Airport to Pittsburgh International Airport via Chicago Midway
- Ave. Duration
- 8h 10m
- When
- Every day
- Estimated price
- $130–650
Flights from Worcester Regional Airport to Pittsburgh International Airport via Orlando
- Ave. Duration
- 7h 16m
- When
- Saturday
- Estimated price
- $190–850
Flights from Boston Logan Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 55m
- When
- Monday to Thursday
- Estimated price
- $100–600
Flights from Bradley International Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $90–550
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $90–550
- Website
- delta.com
Flights from Worcester Regional Airport to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 5h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–470
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $90–550
- Website
- jetblue.com
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $90–550
- Website
- flybreeze.com
Flights from Bradley International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 40m
- When
- Monday and Friday
- Estimated price
- $60–550
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 46m
- When
- Thursday and Sunday
- Estimated price
- $200–1,200
Train from Shirley to Porter
- Ave. Duration
- 59 min
- Frequency
- Every 2 hours
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Train from Shirley to North Station
- Ave. Duration
- 1h 13m
- Frequency
- Every 2 hours
- Estimated price
- $7–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $7–13
Train from Shirley to Porter
- Ave. Duration
- 59 min
- Frequency
- Every 2 hours
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 13m
- Frequency
- Once daily
- Estimated price
- $240–370
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Worcester to New York
- Ave. Duration
- 3h 35m
- Frequency
- 4 times a day
- Estimated price
- $35–60
- Website
- Peter Pan
Bus from Worcester to Hartford
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $12–22
- Website
- Peter Pan
- Phone
- +1-877-462-6342
- [email protected]
- Website
- Megabus
Bus from Port Authority Bus Terminal to Pittsburgh Greyhound
- Ave. Duration
- 7h 50m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Ayer MA to Port Authority Bus Terminal
- Ave. Duration
- 7h 20m
- Frequency
- 5 times a week
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Pittsburgh Intermodal Station
- Ave. Duration
- 7h 40m
- Frequency
- Every 4 hours
- Estimated price
- $70–110
- Website
- Greyhound
- Ave. Duration
- 47 min
- Estimated price
- $45–320
Worcester Green Cab
- Phone
- +1 508-459-1611
Yellow Cab
- Phone
- +1 508-754-3211
- Website
- yellowcabworcester.com
Ready & Ride Transportation Inc.
- Phone
- +1 508 754 1414
- Website
- readyandride.com
Worcester Green Cab
- Phone
- +1 508-459-1611
Yellow Cab
- Phone
- +1 508-754-3211
- Website
- yellowcabworcester.com
Ready & Ride Transportation Inc.
- Phone
- +1 508 754 1414
- Website
- readyandride.com
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Booking & Getting There
Lancaster to Pittsburgh bus services, operated by Peter Pan Bus Lines, arrive at New York station.
Lancaster to Pittsburgh train services, operated by MBTA, arrive at Porter station.
Yes, the driving distance between Lancaster to Pittsburgh is 550 miles. It takes approximately 10h 10m to drive from Lancaster to Pittsburgh.
There are 735+ hotels available in Pittsburgh.






















