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How to get fromLancaster to Buffaloby bus, train, plane, train (Amtrak), or car

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There are 7 ways to get from Lancaster to Buffalo by bus, train, plane, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 18 bus, train to Philadelphia International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Queen St. Station to AMTRAK ETownbus bus
    2. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    7h 31m

  2. Drive 312.6 mi

    cheapest
    1. Drive from Lancaster to Buffalocar car 312.6 mi
    6h 22m
    $57–83

  3. Bus

    1. Take the bus from Harrisburg, Pa to Dubois, Pabus bus 731
    2. Take the bus from DuBois to Buffalobus bus Fab510 / ...
    13h 44m
    $63–211

  4. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    14h 47m
    $197–406

  5. Train to Philadelphia International Airport, fly to Rochester, bus

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    8h 34m
    $160–803

  6. Train, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    8h 29m
    $143–1,335

  7. Train, train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    9h 22m
    $193–1,592

Lancaster to Buffalo by bus and train

Calendar1Weekly Services
Duration13h 44mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Buffalo.ExpandLaunch map view
  • Distance: 407.8 mi
  • Duration: 7h 31m

What companies run services between Lancaster, PA, USA and Buffalo, NY, USA?

You can take a bus from Queen St. Station to Buffalo via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg, Pa, and DuBois in around 13h 44m. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Buffalo via AMTRAK ETown, Elizabethtown Amtrak Station, and Ny Moynihan Train Hall At Penn Station in around 14h 47m.

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