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How to get fromLancaster to Cambridgeby train (Amtrak), train, bus, car, plane, or bus (Greyhound)

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There are 9 ways to get from Lancaster to Cambridge by train (Amtrak), train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Elizabethtown Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    9h 29m
    $124–263

  2. Drive 358.3 mi

    cheapest
    1. Drive from Lancaster to Cambridgecar car 358.3 mi
    6h 56m
    $66–95

  3. Train, bus

    1. Take the train from Elizabethtown Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the bus from New York Midtown to Bostonbus bus FlixBus 2610 / ...
    10h 42m
    $87–171

  4. Line 18 bus to Harrisburg International Airport, fly to Boston Logan Airport

    1. Take the bus from Queen St. Station to AMTRAK ETownbus bus
    2. Fly from Harrisburg International Airport (MDT) to Boston Logan Airport (BOS)plane plane MDT - BOS
    6h 27m

  5. Bus

    1. Take the bus from Harrisburg Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421 / ...
    2. Take the bus from New York, NY - W 42nd Street and 9th Avenue to Boston, MA - Dalton and Belvidere Streetbus bus New York
    13h 39m
    $105–231

  6. Line 18 bus, train to Philadelphia International Airport, fly to Boston Logan Airport

    1. Take the bus from Queen St. Station to AMTRAK ETownbus bus
    2. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Boston Logan Airport (BOS)plane plane PHL - BOS
    6h 59m

  7. Train to Philadelphia International Airport, fly to Manchester Airport, bus

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Manchester Airport (MHT)plane plane PHL - MHT
    3. Take the bus from Boston Manchester Airport to Bostonbus bus
    9h 11m
    $101–513

  8. Train to Philadelphia International Airport, fly to Theodore Francis Green State Airport, train

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Theodore Francis Green State Airport (PVD)plane plane PHL - PVD
    3. Take the train from TF Green Airport to Back Baytrain train
    9h 2m
    $78–364

  9. Train, train to Baltimore-Washington International Airport, fly to Boston Logan Airport

    1. Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Boston Logan Airport (BOS)plane plane BWI - BOS
    8h 31m
    $199–1,714

Lancaster to Cambridge by bus and train (Amtrak)

Calendar27Weekly Services
Duration9h 29mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Cambridge.ExpandLaunch map view
  • Distance: 427.4 mi
  • Duration: 9h 29m

What companies run services between Lancaster, PA, USA and Cambridge, MA, USA?

You can take a bus from W. Walnut & N. Mary St. to Boston via AMTRAK ETown, Elizabethtown Amtrak Station, and Ny Moynihan Train Hall At Penn Station in around 9h 29m. Alternatively, you can take a bus from Queen St. Station to Boston, MA - Dalton and Belvidere Street via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Port Authority Bus Terminal, and New York, NY - W 42nd Street and 9th Avenue in around 13h 39m.

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