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How to get fromLancaster to Charlestonby plane, taxi, bus, train (Amtrak), car, or bus (Flixbus)

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There are 6 ways to get from Lancaster to Charleston by plane, taxi, bus, train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport, taxi

    best
    1. Fly from Harrisburg International Airport (MDT) to University Of Illinois Willard Airport (CMI)plane plane MDT - CMI
    2. Take the taxi from University Of Illinois Willard Airport (CMI) to Charlestontaxi taxi
    11h 6m
    $191–553

  2. Drive 694.1 mi

    cheapest
    1. Drive from Lancaster to Charlestoncar car 694.1 mi
    12h 27m
    $127–183

  3. Bus, taxi (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Effinghambus bus Greyhound US0421
    2. Take the taxi from Effingham to Charlestontaxi taxi
    22h 2m
    $190–321

  4. Train (Amtrak)

    1. Take the train from Elizabethtown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Mattoon Amtrak Stationtrain train
    23h 18m
    $301–651

  5. Fly from Lancaster, taxi

    1. Fly from Lancaster (LNS) to University Of Illinois Willard Airport (CMI)plane plane LNS - CMI
    2. Take the taxi from University Of Illinois Willard Airport (CMI) to Charlestontaxi taxi
    9h 21m
    $188–540

  6. Bus

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago to Phillips Gas Station - Arcolabus bus Chicago / ...
    25h 32m
    $228–429

Harrisburg International Airport (MDT) to University Of Illinois Willard Airport (CMI) flights

Calendar44Weekly Planes
Duration7h 51mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Lancaster to Charleston.ExpandLaunch map view
  • Distance: 701.8 mi
  • Duration: 11h 6m

What companies run services between Lancaster, PA, USA and Charleston, IL, USA?

You can take a bus from W. Walnut & N. Mary St. to Charleston via AMTRAK ETown, Elizabethtown Amtrak Station, Pittsburgh Amtrak Station, Chicago Union Station, and Mattoon Amtrak Station in around 23h 18m. Alternatively, you can take a bus from Queen St. Station to Charleston via AMTRAK ETown, Elizabethtown Amtrak Station, Harrisburg, Harrisburg Bus Station, Chicago Bus Station, Harrison & Jefferson, Cicero & 24th Place Terminal, Chicago, and Phillips Gas Station - Arcola in around 25h 32m.

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