There are 7 ways to get from Lancaster to Chicago by plane, train (Amtrak), bus (Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Lancaster
best- Fly from Lancaster (LNS) to Chicago O'Hare International Airport (ORD)plane LNS - ORD
4h 40m$55–295Train via Pittsburgh (Amtrak)
- Take the train from Elizabethtown Amtrak Station to Pittsburgh Amtrak Stationtrain Pennsylvanian
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
18h 45m$404–630Bus (Flixbus)
- Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus FlixBus N2640 / ...
19h 49m$129–204Drive 691.6 mi
- Drive from Lancaster to Chicagocar 691.6 mi
11h 23m$119–171Line 18 bus to Harrisburg International Airport, fly
- Take the bus from Queen St. Station to AMTRAK ETownbus
- Fly from Harrisburg International Airport (MDT) to Chicago O'Hare International Airport (ORD)plane MDT - ORD
7h 26mBus via Baltimore (Greyhound)
- Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus Greyhound US0430 / ...
- Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus Greyhound US0164
27h 4m$166–269Train (Amtrak)
- Take the train from Elizabethtown Amtrak Station to 30th Street Stationtrain Keystone Service / ...
- Take the train from 30th Street Station to Chicago Union Stationtrain Cardinal
31h 37m$597–971
Lancaster to Chicago by bus and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Lancaster to Chicago is to drive which costs $110 - $180 and takes 11h 23m.
The fastest way to get from Lancaster to Chicago is to fly which takes 4h 40m and costs $55 - $300.
No, there is no direct bus from Lancaster station to Chicago station. However, there are services departing from Queen St. Station and arriving at Chicago Bus Station via Harrisburg Bus Station. The journey, including transfers, takes approximately 19h 49m.
No, there is no direct train from Lancaster station to Chicago station. However, there are services departing from Elizabethtown Amtrak Station and arriving at Chicago Union Station via Pittsburgh Amtrak Station. The journey, including transfers, takes approximately 18h 45m.
The distance between Lancaster and Chicago is 646 miles. The road distance is 695.6 miles.
The best way to get from Lancaster to Chicago without a car is to train via Pittsburgh which takes 18h 45m and costs $400 - $650.
It takes approximately 4h 40m to get from Lancaster to Chicago, including transfers.
Lancaster to Chicago bus services, operated by Flixbus USA, depart from Harrisburg Bus Station.
Lancaster to Chicago train services, operated by Amtrak, depart from Elizabethtown Amtrak Station.
The best way to get from Lancaster to Chicago is to fly which takes 4h 40m and costs $55 - $300. Alternatively, you can train via Pittsburgh, which costs $400 - $650 and takes 18h 45m, you could also bus, which costs $120 - $210 and takes 19h 49m.
What companies run services between Lancaster, PA, USA and Chicago, IL, USA?
United Airlines flies from Lancaster (LNS) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a bus from W. Walnut & N. Mary St. to Chicago Union Station via AMTRAK ETown, Elizabethtown Amtrak Station, and Pittsburgh Amtrak Station in around 18h 45m.
- Website
- united.com
Flights from Lancaster to Chicago O'Hare International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $50–290
Flights from Harrisburg International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- $50–290
Flights from Harrisburg International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $55–300
- Website
- aa.com
Flights from Harrisburg International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $50–290
Flights from Harrisburg International Airport to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $55–310
Flights from Harrisburg International Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 1m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $70–350
- Website
- delta.com
Flights from Harrisburg International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- $50–290
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 5h 59m
- Frequency
- Once daily
- Estimated price
- $140–220
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $260–410
- Website
- Amtrak
Train from Elizabethtown Amtrak Station to 30th Street Station
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from 30th Street Station to Chicago Union Station
- Ave. Duration
- 27h 10m
- Frequency
- 3 times a week
- Estimated price
- $550–900
- Website
- Amtrak
#mediaviewer/File:Amtrak_%22Pennsylvanian%22_at_Bryn_Mawr,_PA.jpg "Pennsylvanian exterior")
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Harrisburg Bus Station to Chicago Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- 3 times a day
- Estimated price
- $120–190
- Schedules at
- Flixbus USA
- Phone
- +1 717-397-4246
- Website
- Red Rose Transit
Bus from Queen St. Station to AMTRAK ETown
- Ave. Duration
- 1h 2m
- Frequency
- 4 times a day
- Website
- Red Rose Transit
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Harrisburg Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Chicago Bus Station
- Ave. Duration
- 18h 40m
- Frequency
- 4 times a day
- Estimated price
- $130–210
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Lancaster to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Chicago is 1h behind Lancaster. It is currently 8:47 AM in Lancaster and 7:47 AM in Chicago.
Lancaster to Chicago train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Lancaster to Chicago is 696 miles. It takes approximately 11h 23m to drive from Lancaster to Chicago.
Book your Lancaster to Chicago train tickets online with Omio.
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